Triethyl phosphonoacetate

• Catalog No.: 79525
• CAS Number: 867-13-0
• M. F.: C8H17O5P
• M. W.: 224.191341
• Purity: ≥97.0% (GC)

SYNONYMS

• Title: 膦酰基乙酸三乙酯
• IUPAC name: ethyl 2-(diethoxyphosphoryl)acetate
• IUPAC Traditional name: triethyl phosphonoacetate
• Synonyms: 羧甲基膦酸三乙酯; Triethyl carboxymethylphosphonate; 乙氧基羰酰甲基膦酸二乙酯; (Diethoxyphosphinyl)acetic acid ethyl ester; Diethyl ethoxycarbonylmethylphosphonate; NSC 13898; NSC 16128

DATABASE IDS

• Beilstein Number: 1343714
• EC Number: 212-757-6
• PubChem SID: 24887466
• MDL Number: MFCD00009177
• CAS Number: 867-13-0

PROPERTIES

• Grade: purum
• Linear Formula: (C2H5O)2P(O)CH2CO2C2H5
• Purity: ≥97.0% (GC)
• Boiling Point: 142-145 °C/9 mmHg(lit.)
• Density: 1.13 g/mL at 25 °C(lit.)
• Flash Point: 105 °C
• Flash Point: 221 °F
• Refractive Index: n20/D 1.431(lit.)
• Refractive Index: n20/D 1.432
• European Hazard Symbols: Nature polluting (N)
• Personal Protective Equipment: Eyeshields, Gloves
• RID/ADR: UN 3082 9/PG 3
• Risk Statements: 51/53
• RTECS: AG9800000
• Safety Statements: 61
• Hazard Class: 9
• UN Number: 3082
• Packing Group: 3
• German water hazard class: 3

DETAILS

Description (English)

Other Notes
A Horner-Wittig reagent, review7,8; Improved procedure for the C2 homologation of esters to α,β-unsaturated esters9; Synthesis of α-(hydroxymethyl)acrylate10
Application
Reactant involved in:
• Horner-Wadsworth-Emmons reactions1,2
• Intramolecular Heck-type cyclization and isomerizations3
• Tsuji-Trost type reactions4
• Intramolecular aryne-ene reactions5
• Synthesis of aldehydes6

Description (简体中文)

Other Notes
Horner-Wittig 试剂，综述7,8；可改善酯的 C2 同系化反应生成 α,β-不饱和酯的过程9；合成 α-(羟甲基)丙烯酸酯10
Application
Reactant involved in:
• Horner-Wadsworth-Emmons reactions1,2
• Intramolecular Heck-type cyclization and isomerizations3
• Tsuji-Trost type reactions4
• Intramolecular aryne-ene reactions5
• Synthesis of aldehydes6