XTT sodium salt

• Catalog No.: X4251
• CAS Number: 111072-31-2
• M. F.: C22H16N7NaO13S2
• M. W.: 673.52131
• Purity: ≥90%

SYNONYMS

• Title: XTT 钠盐
• IUPAC name: sodium 2,3-bis(2-methoxy-4-nitro-5-sulfonatophenyl)-5-(phenylcarbamoyl)-3H-1,2λ^5,3,4-tetrazol-2-ylium
• IUPAC Traditional name: sodium 2,3-bis(2-methoxy-4-nitro-5-sulfonatophenyl)-5-(phenylcarbamoyl)-1,2λ^5,3,4-tetrazol-2-ylium
• Synonyms: 2,3-Bis(2-methoxy-4-nitro-5-sulfophenyl)-2H-tetrazolium-5-carboxanilide inner salt; 2,3-双(2-甲氧基-4-硝基-5-磺苯基)-2H-四唑-5-甲酰胺内盐 内盐

DATABASE IDS

• CAS Number: 111072-31-2
• PubChem SID: 24902147
• MDL Number: MFCD00083517

PROPERTIES

• Empirical Formula (Hill Notation): C22H16N7NaO13S2
• Purity: ≥90%
• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• Storage Temperature: 2-8°C
• German water hazard class: 3

DETAILS

Description (English)

Application
Useful in AIDS and cancer testing.1
XTT has been used in conjunction with phenazine methosulfate (PMS) to screen human cancer cell lines.1 The tetrazolium dye has also been used to study fungal cell damage, in testing antimicrobial susceptibility of staphylococci, and in Candida biofilm research. Limitations to the XTT assay have been reported.
Principle
In living cells, XTT is metabolically reduced to produce a colorimetric, water-soluble formazan product.

Description (简体中文)

Application
XTT has been used in conjunction with phenazine methosulfate (PMS) to screen human cancer cell lines.1 The tetrazolium dye has also been used to study fungal cell damage, in testing antimicrobial susceptibility of staphylococci, and in Candida biofilm research. Limitations to the XTT assay have been reported.
对于艾滋病和癌症的检测有用。1
Principle
In living cells, XTT is metabolically reduced to produce a colorimetric, water-soluble formazan product.