Ketanserin (+)-tartrate salt

• Catalog No.: 15850
• CAS Number: 83846-83-7
• M. F.: C26H28FN3O9
• M. W.: 545.5136232
• Purity: ≥98.0% (TLC)

SYNONYMS

• IUPAC name: (2R,3R)-2,3-dihydroxybutanedioic acid; 3-{2-[4-(4-fluorobenzoyl)piperidin-1-yl]ethyl}-1,2,3,4-tetrahydroquinazoline-2,4-dione
• IUPAC Traditional name: L(+)-tartaric acid; ketanserin
• Synonyms: R 41468 (+)-tartrate salt; 3-(2-[4-(4-Fluorobenzoyl)-1-piperidinyl]ethyl)-2,4(1H,3H)-quinazolinedione (+)-tartrate salt

DATABASE IDS

• EC Number: 281-062-8
• CAS Number: 83846-83-7
• MDL Number: MFCD00084651

PROPERTIES

• Empirical Formula (Hill Notation): C22H22FN3O3 · C4H6O6
• Purity: ≥98.0% (TLC)
• GHS Signal Word: Danger
• GHS Hazard statements: H301
• European Hazard Symbols: Toxic (T)
• Personal Protective Equipment: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
• GHS Precautionary statements: P301 + P310
• RID/ADR: UN 2811 6.1/PG 3
• Risk Statements: 25
• RTECS: VA1411195
• Safety Statements: 22-36/37/39-45
• Hazard Class: 6.1
• UN Number: 2811
• Packing Group: 3
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Selective 5-HT2 serotonin receptor antagonist. Ketanserin significantly reduces nicotine self-administration in rats, supporting an unexpected involvement of serotonin in nicotine addiction.1

Description (简体中文)

Biochem/physiol Actions
Selective 5-HT2 serotonin receptor antagonist. Ketanserin significantly reduces nicotine self-administration in rats, supporting an unexpected involvement of serotonin in nicotine addiction.1