Scutellarin

• Catalog No.: 73577
• CAS Number: 27740-01-8
• M. F.: C21H18O12
• M. W.: 462.36042
• Purity: ≥98.0% (HPLC)

SYNONYMS

• IUPAC name: (2S,3S,4S,5R,6S)-6-{[5,6-dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-7-yl]oxy}-3,4,5-trihydroxyoxane-2-carboxylic acid
• IUPAC Traditional name: scutellarin
• Synonyms: 7-(β-D-Glucopyranuronosyloxy)-5,6-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one; 5,6-Dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-1-benzopyran-7-yl-β-D-glucopyranosiduronic acid; Scutellarein-7-O-β-D-glucuronide; Breviscapin

DATABASE IDS

• MDL Number: MFCD01861503
• Beilstein Number: 71779
• CAS Number: 27740-01-8

PROPERTIES

• Empirical Formula (Hill Notation): C21H18O12
• Grade: analytical standard
• Purity: ≥98.0% (HPLC)
• Shelf Life: (limited shelf life, expiry date on the label)
• Storage Temperature: 2-8°C
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Scutellarin is a flavonoid that exhibits a number of cardio- and neuro-protective effects. Scutellarin inhibits p38 activity, ERK phosphorylation, and TGF-β expression and fibrosis in a rat myocardial infarct model. In a cerebral ischemia-reperfusion model, the compound reduced infarct volume and neurological deficits by increasing eNOS expression while inhibiting the induction of iNOS.

Description (简体中文)

Biochem/physiol Actions
Scutellarin is a flavonoid that exhibits a number of cardio- and neuro-protective effects. Scutellarin inhibits p38 activity, ERK phosphorylation, and TGF-β expression and fibrosis in a rat myocardial infarct model. In a cerebral ischemia-reperfusion model, the compound reduced infarct volume and neurological deficits by increasing eNOS expression while inhibiting the induction of iNOS.