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Azithromycin dihydrate

Catalog No. 57947 Name Sigma Aldrich
CAS Number 117772-70-0 Website http://www.sigmaaldrich.com
M. F. C38H76N2O14 Telephone 1-800-521-8956
M. W. 785.01504 Fax
Purity Email
Storage Chembase ID: 154613

SYNONYMS

Title
阿齐霉素 二水合物
IUPAC name
(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-11-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy}-2-ethyl-3,4,10-trihydroxy-13-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy}-3,5,6,8,10,12,14-heptamethyl-1-oxa-6-azacyclopentadecan-15-one dihydrate
IUPAC Traditional name
azithromycin dihydrate
Synonyms
CP-62993
N-Methyl-11-aza-10-deoxo-10-dihydroerythromycin A

DATABASE IDS

MDL Number MFCD01862248
CAS Number 117772-70-0

PROPERTIES

Empirical Formula (Hill Notation) C38H72N2O12 · 2H2O
Pharmacopeia Traceability traceable to PhEur Y0000307
Pharmacopeia Traceability traceable to USP 1046056
MSDS Link Download
Storage Temperature -20°C
German water hazard class 3

DETAILS

Description (English)
Biochem/physiol Actions
Azithromycin dihydrate is a macrolide antibiotic, azalide subclass. It binds to the 50S subunit of the 70S bacterial ribosomes and inhibits RNA-dependent protein synthesis in bacterial cells. Azithromycin also has anti-immunomodulatory/anti-inflammatory properties, which make it useful in treating cystic fibrosis.
Description (简体中文)
Biochem/physiol Actions
Azithromycin dihydrate is a macrolide antibiotic, azalide subclass. It binds to the 50S subunit of the 70S bacterial ribosomes and inhibits RNA-dependent protein synthesis in bacterial cells. Azithromycin also has anti-immunomodulatory/anti-inflammatory properties, which make it useful in treating cystic fibrosis.

REFERENCES