[6]-Gingerol

• Catalog No.: 50866
• CAS Number: 23513-14-6
• M. F.: C17H26O4
• M. W.: 294.38594
• Purity: ≥95.0% (HPLC)

SYNONYMS

• Title: 6-姜酚
• IUPAC name: (5S)-5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)decan-3-one
• IUPAC Traditional name: gingerol
• Synonyms: 6-Gingerol; 姜辣素; 3-Decanone, 5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-, (5S)-; 5-Hydroxy-1-(4-hydroxy-3-methoxyphenyl)-3-decanone; 5-羟基-1-(4-羟基-3-甲氧基苯基)-3-癸酮; 6-姜辣醇

DATABASE IDS

• CAS Number: 23513-14-6
• MDL Number: MFCD00210507

PROPERTIES

• Empirical Formula (Hill Notation): C17H26O4
• Grade: analytical standard
• Purity: ≥95.0% (HPLC)
• Shelf Life: (expiry date on the label)
• GHS Signal Word: Danger
• GHS Hazard statements: H301-H315-H319-H335
• European Hazard Symbols: Harmful (Xn)
• GHS Precautionary statements: P261-P301 + P310-P305 + P351 + P338
• Risk Statements: 22-36/37/38
• RTECS: HE0757000
• Safety Statements: 26-36/37
• Storage Temperature: 2-8°C
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Bioactive compound found in ginger (Zingiber officinale) with antioxidant activity,1 which functions as an anti-inflammatory and antitumor agent. [6]-Gingerol down regulates proinflammatory cytokine release by macrophages.2 It has been shown to inhibit COX-2 expression by blocking the activation of p38 MAP kinase and NF-κB in phorbol ester-stimulated mouse skin.3

Description (简体中文)

Biochem/physiol Actions
存在于生姜 (Zingiber officinale) 中的具有抗氧化活性的生物活性化合物，1可用作抗炎剂和抗肿瘤剂。6-姜酚通过巨噬细胞下调促炎细胞因子的释放。2已证明它可通过阻断经佛波酯刺激的小鼠皮肤中 p38 MAP 激酶和 NF-κB 的活化来抑制 COX-2 的表达。3