Norfloxacin

• Catalog No.: 33899
• CAS Number: 70458-96-7
• M. F.: C16H18FN3O3
• M. W.: 319.3308232

SYNONYMS

• Title: 诺氟沙星
• IUPAC name: 1-ethyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid
• IUPAC Traditional name: norfloxacin
• Synonyms: 1-乙基-6-氟-1,4-二氢-4-氧代-7-哌嗪-3-喹啉羧酸; 1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid; 1-乙基-6-氟-1,4-二氢-4-氧代-7-(1-哌嗪基)-3-喹啉羧酸; 1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-piperazino-3-quinolinecarboxylic acid

DATABASE IDS

• EC Number: 274-614-4
• CAS Number: 70458-96-7
• PubChem SID: 24860599
• MDL Number: MFCD00079532

PROPERTIES

• Empirical Formula (Hill Notation): C16H18FN3O3
• Grade: VETRANAL™, analytical standard
• Suitability: suitable for 1694 per US EPA
• Gene Information: human ... CYP1A2(1544)rat ... Gabra1(29705)
• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• RTECS: VB2005000
• Storage Temperature: 2-8°C
• German water hazard class: 2

DETAILS

Description (English)

Biochem/physiol Actions
Norfloxacin blocks DNA replication by interfering with an ATP-induced structural transition of DNA complexed with DNA gyrase (topoisomerase).Mode of action: inhibits bacterial DNA replicationAntimicrobial spectrum: Gram-negative bacteria; less effective against Gram-positive bacteria
Legal Information
VETRANAL is a trademark of Sigma-Aldrich Co. LLC

Description (简体中文)

Biochem/physiol Actions
Norfloxacin blocks DNA replication by interfering with an ATP-induced structural transition of DNA complexed with DNA gyrase (topoisomerase).Mode of action: inhibits bacterial DNA replicationAntimicrobial spectrum: Gram-negative bacteria; less effective against Gram-positive bacteria
法律信息
VETRANAL 商标 Sigma-Aldrich Co. LLC