Capsaicin

• Catalog No.: 12084
• CAS Number: 404-86-4
• M. F.: C18H27NO3
• M. W.: 305.41188
• Purity: ≥99.0% (HPLC)

SYNONYMS

• Title: 辣椒碱
• IUPAC name: N-[(4-hydroxy-3-methoxyphenyl)methyl]-8-methylnon-6-enamide
• IUPAC Traditional name: N-[(4-hydroxy-3-methoxyphenyl)methyl]-8-methylnon-6-enamide
• Synonyms: 8-甲基-N-香草基-反-6-壬烯酰胺; 8-Methyl-N-vanillyl-trans-6-nonenamide

DATABASE IDS

• MDL Number: MFCD00017259
• Beilstein Number: 2816484
• PubChem SID: 24847432
• CAS Number: 404-86-4
• EC Number: 206-969-8

PROPERTIES

• Linear Formula: (CH3)2CHCH=CH(CH2)4CONHCH2C6H3-4-(OH)-3-(OCH3)
• Purity: ≥99.0% (HPLC)
• Flash Point: 113 °C
• Flash Point: 235.4 °F
• Melting Point: 62-65 °C(lit.)
• GHS Signal Word: Danger
• GHS Hazard statements: H301-H315-H317-H318-H334-H335
• European Hazard Symbols: Toxic (T)
• Personal Protective Equipment: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
• GHS Precautionary statements: P261-P280-P301 + P310-P305 + P351 + P338-P342 + P311
• RID/ADR: UN 2811 6.1/PG 2
• Risk Statements: 25-37/38-41-42/43
• RTECS: RA8530000
• Safety Statements: 22-26-28-36/39-45
• Storage Temperature: 2-8°C
• Hazard Class: 6.1
• UN Number: 2811
• Packing Group: 2
• German water hazard class: 3

DETAILS

Description (简体中文)

Biochem/physiol Actions
Prototype vanilloid receptor agonist. Neurotoxin; activates sensory neurons that give rise to unmyelinated C-fibers, many of which contain substance P. Topical application desensitizes the sensory nerve endings giving a paradoxical antinociceptive effect; systemic administration can be neurotoxic to capsaicin-sensitive cells, especially in newborn animals. Active component of chili peppers.

Description (English)

Biochem/physiol Actions
Prototype vanilloid receptor agonist. Neurotoxin; activates sensory neurons that give rise to unmyelinated C-fibers, many of which contain substance P. Topical application desensitizes the sensory nerve endings giving a paradoxical antinociceptive effect; systemic administration can be neurotoxic to capsaicin-sensitive cells, especially in newborn animals. Active component of chili peppers.