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Capsaicin

Catalog No. 12084 Name Sigma Aldrich
CAS Number 404-86-4 Website http://www.sigmaaldrich.com
M. F. C18H27NO3 Telephone 1-800-521-8956
M. W. 305.41188 Fax
Purity ≥99.0% (HPLC) Email
Storage Chembase ID: 72832

SYNONYMS

Title
辣椒碱
IUPAC name
N-[(4-hydroxy-3-methoxyphenyl)methyl]-8-methylnon-6-enamide
IUPAC Traditional name
N-[(4-hydroxy-3-methoxyphenyl)methyl]-8-methylnon-6-enamide
Synonyms
8-甲基-N-香草基-反-6-壬烯酰胺
8-Methyl-N-vanillyl-trans-6-nonenamide

DATABASE IDS

MDL Number MFCD00017259
Beilstein Number 2816484
PubChem SID 24847432
CAS Number 404-86-4
EC Number 206-969-8

PROPERTIES

Linear Formula (CH3)2CHCH=CH(CH2)4CONHCH2C6H3-4-(OH)-3-(OCH3)
Purity ≥99.0% (HPLC)
Flash Point 113 °C
Flash Point 235.4 °F
Melting Point 62-65 °C(lit.)
GHS Pictograms GHS05
GHS Pictograms GHS06
GHS Pictograms GHS08
GHS Signal Word Danger
GHS Hazard statements H301-H315-H317-H318-H334-H335
European Hazard Symbols Toxic Toxic (T)
MSDS Link Download
Personal Protective Equipment Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
GHS Precautionary statements P261-P280-P301 + P310-P305 + P351 + P338-P342 + P311
RID/ADR UN 2811 6.1/PG 2
Risk Statements 25-37/38-41-42/43
RTECS RA8530000
Safety Statements 22-26-28-36/39-45
Storage Temperature 2-8°C
Hazard Class 6.1
UN Number 2811
Packing Group 2
German water hazard class 3

DETAILS

Description (简体中文)
Biochem/physiol Actions
Prototype vanilloid receptor agonist. Neurotoxin; activates sensory neurons that give rise to unmyelinated C-fibers, many of which contain substance P. Topical application desensitizes the sensory nerve endings giving a paradoxical antinociceptive effect; systemic administration can be neurotoxic to capsaicin-sensitive cells, especially in newborn animals. Active component of chili peppers.
Description (English)
Biochem/physiol Actions
Prototype vanilloid receptor agonist. Neurotoxin; activates sensory neurons that give rise to unmyelinated C-fibers, many of which contain substance P. Topical application desensitizes the sensory nerve endings giving a paradoxical antinociceptive effect; systemic administration can be neurotoxic to capsaicin-sensitive cells, especially in newborn animals. Active component of chili peppers.

REFERENCES