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Chloramphenicol

Catalog No. 31667 Name Sigma Aldrich
CAS Number 56-75-7 Website http://www.sigmaaldrich.com
M. F. C11H12Cl2N2O5 Telephone 1-800-521-8956
M. W. 323.12938 Fax
Purity Email
Storage Chembase ID: 53504

SYNONYMS

Title
氯霉素
IUPAC name
2,2-dichloro-N-[(1R,2R)-1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl]acetamide
IUPAC Traditional name
chloromycetin
Synonyms
D(-)-threo-2,2-Dichloro-N-[β-hydroxy-α-(hydroxymethyl)-β-(4-nitrophenyl)ethyl]acetamide
D-(-)-threo-2-Dichloroacetamido-1-(4-nitrophenyl)-1,3-propanediol
D-threo-2,2-Dichloro-N-[β-hydroxy-α-(hydroxymethyl)-4-nitrophenethyl]acetamide
D-(-)-threo-2,2-Dichloro-N-[β-hydroxy-α-(hydroxymethyl)-β-(4-nitrophenyl)ethyl]acetamide
Chloromycetin

DATABASE IDS

MDL Number MFCD00078159
PubChem SID 24869808
Beilstein Number 2225532
CAS Number 56-75-7
EC Number 200-287-4

PROPERTIES

Grade VETRANAL™, analytical standard
Linear Formula Cl2CHCONHCH(CH2OH)CH(OH)C6H4NO2
Gene Information human ... CYP1A2(1544)
Melting Point 148-150 °C(lit.)
GHS Pictograms GHS08
GHS Signal Word Danger
GHS Hazard statements H350
European Hazard Symbols Toxic Toxic (T)
MSDS Link Download
Personal Protective Equipment Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
GHS Precautionary statements P201-P308 + P313
Risk Statements 45
RTECS AB6825000
Safety Statements 53-45
German water hazard class 3

DETAILS

Description (English)
Biochem/physiol Actions
Mode of Action: Inhibits translation on the 50S ribosomal subunit at the peptidyltransferase step (elongation inhibition). Bacteriostatic.Mode of Resistance: Acetylation by chloramphenicol acetyltransferase (cat gene).
General description
Standard for Supelco MIP SPE cartridges. For more information request Supelco Literature T407075, T706024
Legal Information
VETRANAL is a trademark of Sigma-Aldrich Co. LLC
Description (简体中文)
Biochem/physiol Actions
Mode of Action: Inhibits translation on the 50S ribosomal subunit at the peptidyltransferase step (elongation inhibition). Bacteriostatic.Mode of Resistance: Acetylation by chloramphenicol acetyltransferase (cat gene).
General description
Supelco MIP SPE 滤筒标准品。更多信息,请参阅 Supelco 文献 T407075 和 T706024。
法律信息
VETRANAL 商标 Sigma-Aldrich Co. LLC

REFERENCES