Calcium Ionophore A23187 hemicalcium salt

• Catalog No.: 21046
• CAS Number: 59450-89-4
• M. F.: C58H72CaN6O12
• M. W.: 1085.30328
• Purity: ≥98.0% (TLC)

SYNONYMS

• Title: 钙离子载体 A23187 半钙盐
• IUPAC name: [5-(methylamino)-2-{[(2R,3R,8S,9R,11R)-3,9,11-trimethyl-8-[(2S)-1-oxo-1-(1H-pyrrol-2-yl)propan-2-yl]-1,7-dioxaspiro[5.5]undecan-2-yl]methyl}-1,3-benzoxazole-4-carbonyloxy]calcio 5-(methylamino)-2-{[(2R,3R,6S,8S,9R,11R)-3,9,11-trimethyl-8-[(2S)-1-oxo-1-(1H-pyrrol-2-yl)propan-2-yl]-1,7-dioxaspiro[5.5]undecan-2-yl]methyl}-1,3-benzoxazole-4-carboxylate
• IUPAC Traditional name: [5-(methylamino)-2-{[(2R,3R,8S,9R,11R)-3,9,11-trimethyl-8-[(2S)-1-oxo-1-(1H-pyrrol-2-yl)propan-2-yl]-1,7-dioxaspiro[5.5]undecan-2-yl]methyl}-1,3-benzoxazole-4-carbonyloxy]calcio 5-(methylamino)-2-{[(2R,3R,6S,8S,9R,11R)-3,9,11-trimethyl-8-[(2S)-1-oxo-1-(1H-pyrrol-2-yl)propan-2-yl]-1,7-dioxaspiro[5.5]undecan-2-yl]methyl}-1,3-benzoxazole-4-carboxylate
• Synonyms: Antibiotic A 23187 hemicalcium salt; Calimycin; Antibiotic A 23187; Calcimycin hemicalcium salt; A23187 半钙盐; A23187 hemicalcium salt; Calimycin hemicalcium salt

DATABASE IDS

• CAS Number: 59450-89-4
• Beilstein Number: 6765084
• MDL Number: MFCD00077678

PROPERTIES

• Empirical Formula (Hill Notation): C29H36Ca0.5N3O6
• Impurities: ≤2% water
• Purity: ≥98.0% (TLC)
• Solubility: acetone: soluble10 mg/mL, clear, faintly yellow-green
• GHS Signal Word: Warning
• GHS Hazard statements: H315-H319-H335
• European Hazard Symbols: Irritant (Xi)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves
• GHS Precautionary statements: P261-P305 + P351 + P338
• Risk Statements: 36/37/38
• Safety Statements: 26
• Storage Temperature: 2-8°C
• German water hazard class: 3

DETAILS

Description (English)

Application
Ionophore highly selective for Ca2+. Potentiates responses to NMDA but not quisqualate. In cell culture, stimulates nitric oxide production by calmodulin-dependent constitutive nitric oxide synthase.

Description (简体中文)

Application
Ionophore highly selective for Ca2+. Potentiates responses to NMDA but not quisqualate. In cell culture, stimulates nitric oxide production by calmodulin-dependent constitutive nitric oxide synthase.