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Colchicine

Catalog No. 27650 Name Sigma Aldrich
CAS Number 64-86-8 Website http://www.sigmaaldrich.com
M. F. C22H25NO6 Telephone 1-800-521-8956
M. W. 399.437 Fax
Purity ≥96.0% (HPLC) Email
Storage Chembase ID: 1205

SYNONYMS

Title
秋水仙素
IUPAC name
N-[(10S)-3,4,5,14-tetramethoxy-13-oxotricyclo[9.5.0.02,7]hexadeca-1(16),2,4,6,11,14-hexaen-10-yl]acetamide
IUPAC Traditional name
colchicine

DATABASE IDS

MDL Number MFCD00078484
Beilstein Number 2228813
CAS Number 64-86-8
EC Number 200-598-5

PROPERTIES

Empirical Formula (Hill Notation) C22H25NO6
Impurities ≤10% ethyl acetate + H2O
Impurities ≤3% water
Purity ≥96.0% (HPLC)
Melting Point 150-160 °C (dec.)(lit.)
GHS Pictograms GHS05
GHS Pictograms GHS06
GHS Pictograms GHS08
GHS Signal Word Danger
GHS Hazard statements H300 + H330-H318-H340
European Hazard Symbols Highly toxic Highly toxic (T+)
MSDS Link Download
Personal Protective Equipment Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
GHS Precautionary statements P201-P260-P264-P280-P284-P301 + P310
RID/ADR UN 1544 6.1/PG 1
Risk Statements 46-28
RTECS GH0700000
Safety Statements 53-45
Hazard Class 6.1
UN Number 1544
Packing Group 1
German water hazard class 3

DETAILS

Description (English)
Other Notes
Binds specifically with tubulin thus interfering with microtubule organization.1
Description (简体中文)
Other Notes
Binds specifically with tubulin thus interfering with microtubule organization.1

REFERENCES