N-Methyl-L-prolinol

• Catalog No.: 68890
• CAS Number: 34381-71-0
• M. F.: C6H13NO
• M. W.: 115.17352
• Purity: ≥99.0% (sum of enantiomers, GC)

SYNONYMS

• Title: N-甲基-L-脯氨醇
• IUPAC name: [(2S)-1-methylpyrrolidin-2-yl]methanol
• IUPAC Traditional name: [(2S)-1-methylpyrrolidin-2-yl]methanol
• Synonyms: (S)-2-羟甲基-1-甲基吡咯烷; (S)-2-Hydroxymethyl-1-methylpyrrolidine

DATABASE IDS

• CAS Number: 34381-71-0
• Beilstein Number: 79851
• PubChem SID: 24885858
• EC Number: 251-981-9
• MDL Number: MFCD00011727

PROPERTIES

• Empirical Formula (Hill Notation): C6H13NO
• Grade: purum
• Purity: ≥99.0% (sum of enantiomers, GC)
• Boiling Point: 67-69 °C/12 mmHg(lit.)
• Density: 0.968 g/mL at 25 °C(lit.)
• Flash Point: 63 °C
• Flash Point: 145.4 °F
• Optical Rotation: [α]20/D -51±1°, c = 5% in methanol
• Refractive Index: n20/D 1.469(lit.)
• Refractive Index: n20/D 1.469
• Personal Protective Equipment: Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
• Storage Temperature: -20°C
• German water hazard class: 3

DETAILS

Description (English)

Other Notes
Chiral ligand used in the enantioface conjugate addition of cuprates to enones1,2; Used as starting material for the preparation of (S)-2-cyanomethyl-1-methylpyrrolidine without loss of optical purity3; Intermediate in an optically active alkaloid synthesis4; Preparation of (S)-prophos5

Description (简体中文)

Other Notes
手性配体，用于铜酸盐的对映面共轭加成反应生成烯酮1,2；制备 (S)-2-氰甲基-1-甲基吡咯烷的原料，反应不会损耗光学纯度3；合成光学活性生物碱的中间体4；制备 (S)-灭线磷5