β,β,β-Trichloro-tert-butyl chloroformate

• Catalog No.: 23259
• CAS Number: 66270-36-8
• M. F.: C5H6Cl4O2
• M. W.: 239.91194
• Purity: ≥97.0% (GC)

SYNONYMS

• Title: β,β,β-三氯叔丁基氯甲酸酯
• IUPAC name: 1,1,1-trichloro-2-methylpropan-2-yl chloroformate
• IUPAC Traditional name: 1,1,1-trichloro-2-methylpropan-2-yl chloroformate
• Synonyms: TCBoc-chloride; β,β,β-三氯叔丁氧基羰酰氯; β,β,β-Trichloro-tert-butoxycarbonyl chloride

DATABASE IDS

• CAS Number: 66270-36-8
• Beilstein Number: 1935464
• EC Number: 266-293-4
• MDL Number: MFCD00000801
• PubChem SID: 24853915

PROPERTIES

• Grade: purum
• Linear Formula: ClCO2C(CH3)2CCl3
• Purity: ≥97.0% (GC)
• Boiling Point: 83-84 °C/14 mmHg(lit.)
• Melting Point: 28-30 °C(lit.)
• Melting Point: 28-30 °C
• GHS Signal Word: Danger
• GHS Hazard statements: H301-H311-H314-H331
• European Hazard Symbols: Toxic (T)
• Personal Protective Equipment: Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
• GHS Precautionary statements: P261-P280-P305 + P351 + P338-P310
• RID/ADR: UN 2928 6.1/PG 2
• Risk Statements: 23/24/25-34
• Safety Statements: 26-36/37/39-45
• Hazard Class: 6.1
• UN Number: 2928
• Packing Group: 2
• German water hazard class: 3

DETAILS

Description (English)

Other Notes
Reagent to introduce the TCBOC-amino-protecting group which is stable towards basic and acidic conditions but cleaved by "super-nucleophiles" or by zinc in acetic acid1,2,3,4

Description (简体中文)

Other Notes
引入 TCBOC-氨基保护基团的试剂，该基团在碱性和酸性条件下均稳定，但在乙酸中可被"超亲核试剂"或锌裂解1,2,3,4