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N-(2-Aminoethyl)-5-isoquinolinesulfonamide hydrochloride_Molecular_structure_CAS_116970-50-4)
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N-(2-Aminoethyl)-5-isoquinolinesulfonamide hydrochloride

Catalog No. 06725 Name Sigma Aldrich
CAS Number 116970-50-4 Website http://www.sigmaaldrich.com
M. F. C11H14ClN3O2S Telephone 1-800-521-8956
M. W. 287.76576 Fax
Purity ≥97.0% (HPLC) Email
Storage Chembase ID: 156506

SYNONYMS

IUPAC name
N-(2-aminoethyl)isoquinoline-5-sulfonamide hydrochloride
IUPAC Traditional name
N-(2-aminoethyl)isoquinoline-5-sulfonamide hydrochloride
Synonyms
H-9

DATABASE IDS

Beilstein Number 6548866
CAS Number 116970-50-4
MDL Number MFCD00083242

PROPERTIES

Empirical Formula (Hill Notation) C11H13N3O2S · HCl
Purity ≥97.0% (HPLC)
Solubility methanol: soluble1 mg/mL, clear, colorless
GHS Pictograms GHS07
GHS Signal Word Warning
GHS Hazard statements H302-H315-H319-H335
European Hazard Symbols Irritant Irritant (Xi)
MSDS Link Download
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
GHS Precautionary statements P261-P305 + P351 + P338
Risk Statements 36/37/38
RTECS NX4897000
Safety Statements 26-36
German water hazard class 3

DETAILS

Description (English)
Biochem/physiol Actions
Selective casein kinase 1 inhibitor1. Potent inhibitor of histamine release from human basophils when induced by phorbol ester or DiC8, but not when induced by anti-IgE, fMLP (formyl-Met-Leu-Phe) and calcium ionophore A23187.2 This implicates divergent pathways of basophil activation.
Description (简体中文)
Biochem/physiol Actions
Selective casein kinase 1 inhibitor1. Potent inhibitor of histamine release from human basophils when induced by phorbol ester or DiC8, but not when induced by anti-IgE, fMLP (formyl-Met-Leu-Phe) and calcium ionophore A23187.2 This implicates divergent pathways of basophil activation.

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