Erythromycin

• Catalog No.: 45673
• CAS Number: 114-07-8
• M. F.: C37H67NO13
• M. W.: 733.92678
• Purity: ≥95.0% (NT)

SYNONYMS

• Title: 红霉素
• IUPAC name: (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy}-14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy}-3,5,7,9,11,13-hexamethyl-1-oxacyclotetradecane-2,10-dione
• IUPAC Traditional name: erythromycin

DATABASE IDS

• CAS Number: 114-07-8
• MDL Number: MFCD00084654
• PubChem SID: 24869225
• Beilstein Number: 75279
• EC Number: 204-040-1

PROPERTIES

• Empirical Formula (Hill Notation): C37H67NO13
• Purity: ≥95.0% (NT)
• Gene Information: human ... ABCB1(5243), CYP3A4(1576), MLNR(2862)mouse ... Abcb1a(18671), Abcb1b(18669)
• Melting Point: 133-135 °C
• Optical Rotation: [α]20/D -75±4°, c = 2% in ethanol
• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• RTECS: KF437500
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Mode of Action: Inhibits elongation at transpeptidation step.Antimicrobial spectrum: Gram-negative and Gram-positive bacteria.
Other Notes
Macrolide antibiotic.
Inhibits bacterial protein synthesis by binding to the ribosomes1; Inducible erythromycin resistance in bacteria2

Description (简体中文)

Biochem/physiol Actions
Mode of Action: Inhibits elongation at transpeptidation step.Antimicrobial spectrum: Gram-negative and Gram-positive bacteria.
Other Notes
Macrolide antibiotic.
通过结合到核糖体上抑制细菌蛋白合成1；在细菌中可诱导红霉素抗性2