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Captopril

Catalog No. 21751 Name Sigma Aldrich
CAS Number 62571-86-2 Website http://www.sigmaaldrich.com
M. F. C9H15NO3S Telephone 1-800-521-8956
M. W. 217.2853 Fax
Purity ≥99.0% (HPLC) Email
Storage Chembase ID: 1067

SYNONYMS

Title
卡托普利
IUPAC name
(2S)-1-[(2S)-2-methyl-3-sulfanylpropanoyl]pyrrolidine-2-carboxylic acid
IUPAC Traditional name
captopril
Synonyms
N-[(S)-3-巯基-2-甲基丙酰基]-L-脯氨酸
N-[(S)-3-Mercapto-2-methylpropionyl]-L-proline

DATABASE IDS

Beilstein Number 477887
MDL Number MFCD00168073
EC Number 263-607-1
CAS Number 62571-86-2

PROPERTIES

Empirical Formula (Hill Notation) C9H15NO3S
Purity ≥99.0% (HPLC)
Gene Information human ... ACE(1636)
Melting Point 104-108 °C(lit.)
Solubility H2O: soluble0.1 g/mL, very slightly hazy, colorless
GHS Pictograms GHS07
GHS Pictograms GHS08
GHS Signal Word Warning
GHS Hazard statements H317-H361
European Hazard Symbols Harmful Harmful (Xn)
MSDS Link Download
Personal Protective Equipment Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
GHS Precautionary statements P280
Risk Statements 63-43
RTECS UY0550000
Safety Statements 36/37
German water hazard class 3

DETAILS

Description (English)
Biochem/physiol Actions
Angiotensin converting enzyme inhibitor. Inhibits the formation of angiotensin II, a bioactive peptide that stimulates angiogenesis and increases microvessel density.
Description (简体中文)
Biochem/physiol Actions
血管紧张素转换酶抑制剂。抑制血管紧张素 II 的形成,血管紧张素 II 是生物活性多肽,可促进血管生成并增加微血管密度。

REFERENCES