Home > Compound List > Product Information
5-Fluoro-2′-deoxyuridine_Molecular_structure_CAS_50-91-9)
Click picture or here to close

5-Fluoro-2′-deoxyuridine

Catalog No. 46875 Name Sigma Aldrich
CAS Number 50-91-9 Website http://www.sigmaaldrich.com
M. F. C9H11FN2O5 Telephone 1-800-521-8956
M. W. 246.1924432 Fax
Purity ≥98.0% (HPLC) Email
Storage Chembase ID: 207

SYNONYMS

IUPAC name
5-fluoro-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione
IUPAC Traditional name
floxuridine
Synonyms
2′-Deoxy-5-fluorouridine
FUDR
Floxuridine

DATABASE IDS

EC Number 200-072-5
MDL Number MFCD00006530
CAS Number 50-91-9
Beilstein Number 90221

PROPERTIES

Empirical Formula (Hill Notation) C9H11FN2O5
Purity ≥98.0% (HPLC)
Melting Point 148 °C(lit.)
Melting Point 148-150 °C
Optical Rotation [α]20/D +38±1°, c = 1% in H2O
GHS Pictograms GHS06
GHS Signal Word Danger
GHS Hazard statements H301
European Hazard Symbols Harmful Harmful (Xn)
MSDS Link Download
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Faceshields, Gloves
GHS Precautionary statements P301 + P310
RID/ADR UN 2811 6.1/PG 3
Risk Statements 22
RTECS YU7525000
Safety Statements 22-36
Storage Temperature 2-8°C
Hazard Class 6.1
UN Number 2811
Packing Group 3
German water hazard class 3

DETAILS

Description (English)
Biochem/physiol Actions
Antineoplastic drug that acts as a potent inhibitor of thymidylate synthetase1 Resistance to FUdR can develop in cancer cell cultures, among other means, by low-level Mycoplasma infection.2
Other Notes
Inhibits DNA synthesis by prior inhibition of thymidylate synthetase3
Description (简体中文)
Biochem/physiol Actions
Antineoplastic drug that acts as a potent inhibitor of thymidylate synthetase1 Resistance to FUdR can develop in cancer cell cultures, among other means, by low-level Mycoplasma infection.2
Other Notes
Inhibits DNA synthesis by prior inhibition of thymidylate synthetase3

REFERENCES