Nω-Amino-L-arginine 2,4-dinitro-1-naphthol-7-sulfonate salt

• Catalog No.: 06804
• CAS Number: 137361-06-9
• M. F.: C16H21N7O10S
• M. W.: 503.44384
• Purity: ≥98.0% (TLC)

SYNONYMS

• IUPAC name: (2S)-2-amino-5-(3-aminocarbamimidamido)pentanoic acid; 8-hydroxy-5,7-dinitronaphthalene-2-sulfonic acid
• IUPAC Traditional name: (2S)-2-amino-5-(3-aminocarbamimidamido)pentanoic acid; naphthol yellow S
• Synonyms: Nγ-Amino-L-arginine 2,4-dinitro-1-naphthol-7-sulfonate salt

DATABASE IDS

• PubChem SID: 24845974
• MDL Number: MFCD00236796
• CAS Number: 137361-06-9

PROPERTIES

• Empirical Formula (Hill Notation): C6H15N5O2 · C10H6N2O8S
• Purity: ≥98.0% (TLC)
• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• Storage Temperature: 2-8°C
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Inactivates all isoforms of nitric oxide synthase1. The mechanism of NOS inactivation is not well understood, but is believed to affect only enzyme molecules that are actively metabolizing. One study of inactivation of the neuronal isoform (nNOS)2 implicated a covalent modification of the heme prosthetic group and a heme irreversibly bound to the protein.

Description (简体中文)

Biochem/physiol Actions
Inactivates all isoforms of nitric oxide synthase1. The mechanism of NOS inactivation is not well understood, but is believed to affect only enzyme molecules that are actively metabolizing. One study of inactivation of the neuronal isoform (nNOS)2 implicated a covalent modification of the heme prosthetic group and a heme irreversibly bound to the protein.