(-)-Scopolamine hydrobromide trihydrate

• Catalog No.: 84785
• CAS Number: 6533-68-2
• M. F.: C17H28BrNO7
• M. W.: 438.31072
• Purity: ≥98.0% (TLC)

SYNONYMS

• Title: (-)-东莨菪碱 氢溴酸盐 三水合物
• IUPAC name: (1R,2R,4S,5S,7S)-9-methyl-3-oxa-9-azatricyclo[3.3.1.0^2,^4]nonan-7-yl (2S)-3-hydroxy-2-phenylpropanoate trihydrate hydrobromide
• IUPAC Traditional name: (1R,2R,4S,5S,7S)-9-methyl-3-oxa-9-azatricyclo[3.3.1.0^2,^4]nonan-7-yl (2S)-3-hydroxy-2-phenylpropanoate trihydrate hydrobromide
• Synonyms: 莨菪胺; 天仙子碱 氢溴酸盐; Hyoscine hydrobromide; Scopine tropate

DATABASE IDS

• CAS Number: 6533-68-2
• PubChem SID: 24888267
• MDL Number: MFCD00150066
• Beilstein Number: 6100669

PROPERTIES

• Empirical Formula (Hill Notation): C17H21NO4 · HBr · 3H2O
• Grade: purum
• Purity: ≥98.0% (TLC)
• Melting Point: 195-199 °C (dry matter)(lit.)
• Optical Rotation: [α]20/D -23±2°, c = 5% in H2O
• GHS Signal Word: Danger
• GHS Hazard statements: H300-H310-H330
• European Hazard Symbols: Highly toxic (T+)
• Personal Protective Equipment: Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
• GHS Precautionary statements: P260-P264-P280-P284-P301 + P310-P302 + P350
• RID/ADR: UN 1544 6.1/PG 3
• Risk Statements: 26/27/28
• RTECS: YM4730000
• Safety Statements: 25-45
• Hazard Class: 6.1
• UN Number: 1544
• Packing Group: 3
• German water hazard class: 1

DETAILS

Description (English)

Biochem/physiol Actions
Competitive nonselective muscarinic acetylcholine antagonist. Scopolamine-induced amnesia in laboratory animals is a commonly-used model of memory deficit.

Description (简体中文)

Biochem/physiol Actions
竞争性非选择性毒蕈碱型乙酰胆碱拮抗剂。东莨菪碱所致的实验室动物记忆障碍是常用的记忆缺陷模型。