Thio-OMe tricesium salt

• Catalog No.: 29216
• M. F.: C23H18Cs3NO8S
• M. W.: 867.17227

SYNONYMS

• IUPAC name: tricaesium(1+) ion 2-{2-[bis(carboxylatomethyl)amino]-5-[5-(4-methoxyphenyl)thiophen-2-yl]phenoxy}acetate
• IUPAC Traditional name: tricaesium(1+) ion 2-{2-[bis(carboxylatomethyl)amino]-5-[5-(4-methoxyphenyl)thiophen-2-yl]phenoxy}acetate
• Synonyms: 2-Amino-5-[5-(4-methoxyphenyl)-2-thienyl]phenol-N,N,O-triacetic acid tricesium salt

DATABASE IDS

• MDL Number: MFCD03453213
• PubChem SID: 24857563

PROPERTIES

• Empirical Formula (Hill Notation): C23H18Cs3NO8S
• Fluorescence: λex 337 nm; λem 418 nm in 0.1 M Tris pH 8.0, 10 mM Ca2+
• Fluorescence: λex 337 nm; λem 485 nm in 0.1 M Tris pH 8.0 (without Ca2+)
• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• German water hazard class: 3

DETAILS

Description (English)

Features and Benefits
This is a new Calcium indicator with promising properties which provide an excellent addition to fluorescent Ca2+/Mg2+ indicators available already. It is a low-affinity Ca2+-indicators (Kd ca 126 μM). Such indicators are useful for determination of Ca2+ in intracellular compartments [or for monitoring steep increases in intracellular concentration of Ca2+ . The indicator offers the interesting property of being both excitation and emission rationable, thus ratiomeric measurements are possible both in excitations as emission mode.Thio-OMe does also show strong blue shift of emission maximum (485nm to 418 nm) by binding to Ca2+.

Description (简体中文)

Features and Benefits
This is a new Calcium indicator with promising properties which provide an excellent addition to fluorescent Ca2+/Mg2+ indicators available already. It is a low-affinity Ca2+-indicators (Kd ca 126 μM). Such indicators are useful for determination of Ca2+ in intracellular compartments [or for monitoring steep increases in intracellular concentration of Ca2+ . The indicator offers the interesting property of being both excitation and emission rationable, thus ratiomeric measurements are possible both in excitations as emission mode.Thio-OMe does also show strong blue shift of emission maximum (485nm to 418 nm) by binding to Ca2+.