8-Bromoadenosine 3′,5′-cyclic monophosphate sodium salt

• Catalog No.: 16135
• CAS Number: 76939-46-3
• M. F.: C10H10BrN5NaO6P
• M. W.: 430.083831
• Purity: ≥98.0% (HPLC)

SYNONYMS

• IUPAC name: sodium (4aR,6R,7R,7aS)-6-(6-amino-8-bromo-9H-purin-9-yl)-7-hydroxy-2-oxo-hexahydro-1,3,5,2λ^5-furo[3,2-d][1,3,2λ^5]dioxaphosphinin-2-olate
• IUPAC Traditional name: sodium (4aR,6R,7R,7aS)-6-(6-amino-8-bromopurin-9-yl)-7-hydroxy-2-oxo-tetrahydro-4H-1,3,5,2λ^5-furo[3,2-d][1,3,2λ^5]dioxaphosphinin-2-olate
• Synonyms: 8-Br-cAMP

DATABASE IDS

• Beilstein Number: 7739743
• CAS Number: 76939-46-3
• MDL Number: MFCD00005844

PROPERTIES

• Empirical Formula (Hill Notation): C10H10BrN5NaO6P
• Impurities: ≤2% adenosine-3′,5′-cyclophosphate (HPLC)
• Purity: ≥98.0% (HPLC)
• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• Storage Temperature: -20°C
• German water hazard class: 3

DETAILS

Description (English)

Other Notes
Membrane-permeable cAMP analog.
Inhibits the transient expression of firefly luciferase1
Biochem/physiol Actions
Cell-permeable cAMP analog having greater resistance to hydrolysis by phosphodiesterases than cAMP. Activates protein kinase A, inhibits growth, decreases proliferation, increases differentiation, and induces apoptosis of cultured cells.

Description (简体中文)

Other Notes
Membrane-permeable cAMP analog.
Inhibits the transient expression of firefly luciferase1
Biochem/physiol Actions
Cell-permeable cAMP analog having greater resistance to hydrolysis by phosphodiesterases than cAMP. Activates protein kinase A, inhibits growth, decreases proliferation, increases differentiation, and induces apoptosis of cultured cells.