[Hydroxy(tosyloxy)iodo]benzene

• Catalog No.: 56517
• CAS Number: 27126-76-7
• M. F.: C13H13IO4S
• M. W.: 392.20939
• Purity: ≥97.0% (AT)

SYNONYMS

• Title: 羟基甲苯磺酰碘苯
• IUPAC name: hydroxy phenyl 4-methylbenzene-1-sulfonoperoxoyl iodide
• IUPAC Traditional name: hydroxy phenyl 4-methylbenzenesulfonoperoxoyl iodide
• Synonyms: Koser’s reagent; Koser 试剂; Hydroxy(phenyl)iodo tosylate; [Hydroxy(4-toluenesulfonato)iodo]benzene; Iodosobenzene-I-mono-p-toluenesulfonate; HTIB; NSC 294176; Phenyliodosyl hydroxide tosylate; Hydroxy(4-methylbenzenesulfonato-O)phenyliodine; 羟基(甲苯磺酰氧代)碘苯

DATABASE IDS

• CAS Number: 27126-76-7
• MDL Number: MFCD00011547
• Beilstein Number: 2150074

PROPERTIES

• German water hazard class: 3
• GHS Signal Word: Warning
• GHS Hazard statements: H315-H319
• European Hazard Symbols: Irritant (Xi)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves
• GHS Precautionary statements: P305 + P351 + P338
• Risk Statements: 36/38
• Safety Statements: 26-36
• Grade: purum
• Linear Formula: CH3C6H4SO3I(OH)C6H5
• Purity: ≥97.0% (AT)
• Melting Point: 131-137 °C(lit.)
• Melting Point: 131-137 °C

DETAILS

Description (English)

Other Notes
Reagent for the selective syn-1,2-ditosyloxylation of alkenes, tosyloxylation reactions and other transformations 9,10,11
Application
Reactant for:
• Ligand-free palladium-catalyzed Heck-type coupling reactions1
• Preparation of carbodiimides via dehydrosulfurization of thioureas2
• Preparation of nitriles by oxidative conversion of alcohols, aldehydes, and amines3
• Preparation of substituted anilines via aromatic aldoxime reaction4
• Preparation of tetrahydrofurans by oxidative cyclization of homoallylic alcohols5
• Preparation of isoxazoline N-Oxides from β-hydroxyketoximes via oxidative N-O coupling6
• Ring expansion in synthesis of aminopeptidase inhibitors7
• Oxidation and protonation reactions in acidic conditions8

Description (简体中文)

Other Notes
用于烯烃的选择性顺式-1,2-二对甲苯磺酰氧基化反应、对甲苯磺酰氧基化反应和其他转化的试剂9,10,11
Application
Reactant for:
• Ligand-free palladium-catalyzed Heck-type coupling reactions1
• Preparation of carbodiimides via dehydrosulfurization of thioureas2
• Preparation of nitriles by oxidative conversion of alcohols, aldehydes, and amines3
• Preparation of substituted anilines via aromatic aldoxime reaction4
• Preparation of tetrahydrofurans by oxidative cyclization of homoallylic alcohols5
• Preparation of isoxazoline N-Oxides from β-hydroxyketoximes via oxidative N-O coupling6
• Ring expansion in synthesis of aminopeptidase inhibitors7
• Oxidation and protonation reactions in acidic conditions8