Spermidine

• Catalog No.: 85559
• CAS Number: 124-20-9
• M. F.: C7H19N3
• M. W.: 145.24586
• Purity: ≥99.5% (GC)

SYNONYMS

• Title: 亚精胺
• IUPAC name: (4-aminobutyl)(3-aminopropyl)amine
• IUPAC Traditional name: spermidine
• Synonyms: N-(3-氨基丙基)-1,4-丁二胺; 1,8-二氨基-4-氮杂辛烷; N-(3-Aminopropyl)-1,4-diaminobutane; 1,8-Diamino-4-azaoctane

DATABASE IDS

• Beilstein Number: 1698591
• EC Number: 204-689-0
• MDL Number: MFCD00008229
• CAS Number: 124-20-9

PROPERTIES

• Antion Traces: chloride (Cl-): ≤50 mg/kg
• Antion Traces: sulfate (SO42-): ≤50 mg/kg
• Cation Traces: Al: ≤5 mg/kg
• Cation Traces: As: ≤0.1 mg/kg
• Cation Traces: Ba: ≤5 mg/kg
• Cation Traces: Bi: ≤5 mg/kg
• Cation Traces: Ca: ≤10 mg/kg
• Cation Traces: Cd: ≤5 mg/kg
• Cation Traces: Co: ≤5 mg/kg
• Cation Traces: Cr: ≤5 mg/kg
• Cation Traces: Cu: ≤5 mg/kg
• Cation Traces: Fe: ≤5 mg/kg
• Cation Traces: K: ≤50 mg/kg
• Cation Traces: Li: ≤5 mg/kg
• Cation Traces: Mg: ≤5 mg/kg
• Cation Traces: Mn: ≤5 mg/kg
• Cation Traces: Mo: ≤5 mg/kg
• Cation Traces: Na: ≤50 mg/kg
• Cation Traces: Ni: ≤5 mg/kg
• Cation Traces: Pb: ≤5 mg/kg
• Cation Traces: Sr: ≤5 mg/kg
• Cation Traces: Zn: ≤5 mg/kg
• Impurities: insoluble matter, passes filter test
• λ: 1 M in H2O
• Linear Formula: NH2(CH2)3NH(CH2)4NH2
• Product Line: BioUltra
• Purity: ≥99.5% (GC)
• Absorption Wavelength: λ: 260 nm Amax: 0.1
• Absorption Wavelength: λ: 280 nm Amax: 0.05
• Density: 0.925 g/mL at 25 °C(lit.)
• Flash Point: 112 °C
• Flash Point: 233.6 °F
• Melting Point: 23-25 °C
• pH: 12.0-13.5 (25 °C, 1 M in H2O)
• Refractive Index: n20/D 1.479(lit.)
• Solubility: H2O: soluble1 M at 20 °C, clear, colorless
• GHS Signal Word: Danger
• GHS Hazard statements: H314
• European Hazard Symbols: Corrosive (C)
• Personal Protective Equipment: Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
• GHS Precautionary statements: P280-P305 + P351 + P338-P310
• RID/ADR: UN 2735 8/PG 2
• Risk Statements: 34
• RTECS: EJ7000000
• Safety Statements: 26-36/37/39-45
• Hazard Class: 8
• UN Number: 2735
• Packing Group: 2
• German water hazard class: 3

DETAILS

Description (English)

Caution
Solutions should be sterile-filtered, not autoclaved, if sterile solution is necessary. Spermidine deaminates with time; solutions should be stored frozen. Prepare new solutions frequently.
Other Notes
Polyamines: Review1; Inhibitor of arginine decarboxylase2,3; and DNA polymerase4
Biochem/physiol Actions
Inhibits neuronal nitric oxide synthase (nNOS). Binds and precipitates DNA; may be used for purification of DNA binding proteins. Stimulates T4 polynucleotide kinase activity.

Description (简体中文)

Caution
如果需要无菌溶液，则应采用无菌过滤而非高压灭菌。时间一长，亚精胺将发生脱氨基作用；溶液应采用冷冻保存。通常需要配制新溶液。
Other Notes
Polyamines: Review1; Inhibitor of arginine decarboxylase2,3; and DNA polymerase4
Biochem/physiol Actions
Inhibits neuronal nitric oxide synthase (nNOS). Binds and precipitates DNA; may be used for purification of DNA binding proteins. Stimulates T4 polynucleotide kinase activity.