7-Acetoxy-1-methylquinolinium iodide

• Catalog No.: 00871
• CAS Number: 7270-83-9
• M. F.: C12H12INO2
• M. W.: 329.13365
• Purity: ≥98.0% (HPCE)

SYNONYMS

• IUPAC name: 7-(acetyloxy)-1-methylquinolin-1-ium iodide
• IUPAC Traditional name: 7-(acetyloxy)-1-methylquinolin-1-ium iodide
• Synonyms: AMQI

DATABASE IDS

• PubChem SID: 24845095
• MDL Number: MFCD00037374
• CAS Number: 7270-83-9
• Beilstein Number: 4773437

PROPERTIES

• Empirical Formula (Hill Notation): C12H12INO2
• Grade: for fluorescence
• Purity: ≥98.0% (HPCE)
• Shipped in: dry ice
• Fluorescence: λex 403 nm; λem 502 nm in 0.1 M Tris pH 8.0 (after cleavage by acetylcholin esterase)
• Melting Point: 222 °C(lit.)
• Solubility: DMF: soluble
• Solubility: DMSO: soluble
• Solubility: H2O: soluble
• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• Storage Temperature: -20°C
• German water hazard class: 3

DETAILS

Description (English)

Other Notes
Fluorogenic substrate for cholinesterase3,4
Application
AMQI is a fluorescent substrate for acetylcholinesterase with λ excitation and λemission of 320 nm and 410 nm, respectively. Acetylcholinesterase hydrolyzes the fluorogenic substrate to form 7-hydroxy-1-methyl quinoliniom iodide with λ excitation and λ emission of 406 nm and 505 nm, respectively. It has been utilized in fluorometric assays to determine the bioactivity of this enzyme 1,2.

Description (简体中文)

Other Notes
Fluorogenic substrate for cholinesterase3,4
Application
AMQI is a fluorescent substrate for acetylcholinesterase with λ excitation and λemission of 320 nm and 410 nm, respectively. Acetylcholinesterase hydrolyzes the fluorogenic substrate to form 7-hydroxy-1-methyl quinoliniom iodide with λ excitation and λ emission of 406 nm and 505 nm, respectively. It has been utilized in fluorometric assays to determine the bioactivity of this enzyme 1,2.