N-Phthaloyl-L-glutamic acid

• Catalog No.: 79840
• CAS Number: 340-90-9
• M. F.: C13H11NO6
• M. W.: 277.22954
• Purity: ≥98.0% (T)

SYNONYMS

• Title: N-邻苯二甲酰-L-谷氨酸
• IUPAC name: (2S)-2-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)pentanedioic acid
• IUPAC Traditional name: (2S)-2-(1,3-dioxoisoindol-2-yl)pentanedioic acid
• Synonyms: PhGA

DATABASE IDS

• CAS Number: 340-90-9
• PubChem SID: 24887505
• MDL Number: MFCD00066476
• Beilstein Number: 90136

PROPERTIES

• Empirical Formula (Hill Notation): C13H11NO6
• Grade: purum
• Purity: ≥98.0% (T)
• Melting Point: 160-162 °C(lit.)
• Melting Point: 160-162 °C
• Optical Rotation: [α]20/D -48±2°, c = 3% in dioxane
• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• German water hazard class: 3

DETAILS

Description (English)

Other Notes
N-protected derivative of L-glutamic acid. The anhydride (prepared with DCCI or Ac2O without racemization) is used for γ-L-glutamylations1,2,3,4; The phthaloyl protection can be removed mildly5

Description (简体中文)

Other Notes
L-谷氨酸的 N-保护衍生物。其酸酐（无外消旋下通过 DCCI 或 Ac2O 制备）被用于 γ-L-谷氨酰基化1,2,3,4；邻苯二甲酰基保护基可在温和条件下除去5