8-Acetoxypyrene-1,3,6-trisulfonic acid trisodium salt

• Catalog No.: 00879
• CAS Number: 115787-83-2
• M. F.: C18H9Na3O11S3
• M. W.: 566.42177
• Purity: ≥98.0% (TLC)

SYNONYMS

• IUPAC name: trisodium 8-(acetyloxy)pyrene-1,3,6-trisulfonate
• IUPAC Traditional name: trisodium 8-(acetyloxy)pyrene-1,3,6-trisulfonate
• Synonyms: Trisodium-8-acetoxypyrene-1,3,6-trisulfonate; 1-Acetoxypyrene-3,6,8-trisulfonic acid trisodium salt

DATABASE IDS

• PubChem SID: 24845099
• MDL Number: MFCD00135685
• CAS Number: 115787-83-2
• Beilstein Number: 9538267

PROPERTIES

• Empirical Formula (Hill Notation): C18H9Na3O11S3
• Grade: for fluorescence
• Purity: ≥98.0% (TLC)
• Fluorescence: λex 460 nm; λem 510 nm in 0.1 M potassium phosphate pH 8.0 (esterase)
• Melting Point: 238-248 °C (dec.)(lit.)
• Solubility: DMF: soluble
• Solubility: DMSO: soluble
• Solubility: H2O: soluble
• Solubility: methanol: soluble
• GHS Signal Word: Warning
• GHS Hazard statements: H315-H319-H335
• European Hazard Symbols: Irritant (Xi)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves
• GHS Precautionary statements: P261-P305 + P351 + P338
• Risk Statements: 36/37/38
• Safety Statements: 26-36
• Storage Temperature: -20°C
• German water hazard class: 3

DETAILS

Description (English)

Application
suitable as fluorogenic substrate for esterases
A membrane permeable, nonfluorescent reagent 1. This fluorochrome enters the cell cytoplasm, where its acetic group is cleaved by intracellular, nonspecific esterases, which forms the impermeable, fluorescent form of the molecule1. Utilized as a phloem-mobile symplasmic tracer having staining characteristics that differ from the commonly used CFDA (5-(6-)carboxyfluorescein diacetate)1,2,3,4,5.
Other Notes
Highly water soluble enzyme substrate for the fluorimetric assay of esterases at longwave excitation and emission wavelengths6

Description (简体中文)

Application
suitable as fluorogenic substrate for esterases
A membrane permeable, nonfluorescent reagent 1. This fluorochrome enters the cell cytoplasm, where its acetic group is cleaved by intracellular, nonspecific esterases, which forms the impermeable, fluorescent form of the molecule1. Utilized as a phloem-mobile symplasmic tracer having staining characteristics that differ from the commonly used CFDA (5-(6-)carboxyfluorescein diacetate)1,2,3,4,5.
Other Notes
Highly water soluble enzyme substrate for the fluorimetric assay of esterases at longwave excitation and emission wavelengths6