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Creatine

Catalog No. 27890 Name Sigma Aldrich
CAS Number 57-00-1 Website http://www.sigmaaldrich.com
M. F. C4H9N3O2 Telephone 1-800-521-8956
M. W. 131.13316 Fax
Purity ≥99.0% (NT) Email
Storage Chembase ID: 34

SYNONYMS

Title
肌酸
IUPAC name
2-(1-methylcarbamimidamido)acetic acid
IUPAC Traditional name
creatine
Synonyms
α-甲胍乙酸
N-Amidinosarcosine
N-胺肉胺酸
(α-Methylguanido)acetic acid

DATABASE IDS

EC Number 200-306-6
MDL Number MFCD00004282
CAS Number 57-00-1
Beilstein Number 907175

PROPERTIES

Impurities ≤0.5% water
Linear Formula H2NC(=NH)N(CH3)CH2CO2H
Purity ≥99.0% (NT)
Melting Point ~295 °C (dec.)
GHS Pictograms GHS07
GHS Signal Word Warning
GHS Hazard statements H315-H319-H335
European Hazard Symbols Irritant Irritant (Xi)
MSDS Link Download
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
GHS Precautionary statements P261-P305 + P351 + P338
Risk Statements 36/37/38
Safety Statements 26-36
German water hazard class 3

DETAILS

Description (简体中文)
Other Notes
Identification of creatine as a cofactor of thiamine-diphosphate kinase1
Biochem/physiol Actions
Creatine is a nitrogenous compound that acts as a high-energy reservoir for the rapid regeneration of ATP. Approximately 95% of creatine is found in skeletal muscle, primarily as phosphocreatine. Creatine can be acquired through dietary consumption or formed from L-arginine, glycine, and L-methionine in a multi-step reaction that occurs in the kidneys and liver. Creatine is then transported to muscle tissue. Creatine supplementation is used for the enhancement of sports performance, primarily by increasing muscle mass. Creatine is also being investigated as a treatment of neuromuscular diseases, where it may aid in neuroprotection and by improving the cellular bioenergetic state.
Description (English)
Other Notes
Identification of creatine as a cofactor of thiamine-diphosphate kinase1
Biochem/physiol Actions
Creatine is a nitrogenous compound that acts as a high-energy reservoir for the rapid regeneration of ATP. Approximately 95% of creatine is found in skeletal muscle, primarily as phosphocreatine. Creatine can be acquired through dietary consumption or formed from L-arginine, glycine, and L-methionine in a multi-step reaction that occurs in the kidneys and liver. Creatine is then transported to muscle tissue. Creatine supplementation is used for the enhancement of sports performance, primarily by increasing muscle mass. Creatine is also being investigated as a treatment of neuromuscular diseases, where it may aid in neuroprotection and by improving the cellular bioenergetic state.

REFERENCES