4-Aminoindole

• Catalog No.: 08244
• CAS Number: 5192-23-4
• M. F.: C8H8N2
• M. W.: 132.16252
• Purity: ≥98.0% (NT)

SYNONYMS

• Title: 4-氨基吲哚
• IUPAC name: 1H-indol-4-amine
• IUPAC Traditional name: 1H-indol-4-amine
• Synonyms: 4-Indolamine; 4-吲哚胺; (Indol-4-yl)amine

DATABASE IDS

• CAS Number: 5192-23-4
• Beilstein Number: 114919
• MDL Number: MFCD01076559
• PubChem SID: 24846037

PROPERTIES

• Empirical Formula (Hill Notation): C8H8N2
• Grade: purum
• Purity: ≥98.0% (NT)
• Melting Point: 106-109 °C(lit.)
• Melting Point: 107-111 °C
• GHS Signal Word: Warning
• GHS Hazard statements: H315-H319-H335
• European Hazard Symbols: Irritant (Xi)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves
• GHS Precautionary statements: P261-P305 + P351 + P338
• Risk Statements: 36/37/38
• Safety Statements: 26-36
• Storage Temperature: -20°C
• German water hazard class: 3

DETAILS

Description (English)

Application
Reactant for preparation of:
• Inhibitors of bacterial thymidylate synthase1
• Mimetics of non-alkaloid toxin lignan anticancer and antiviral agent Podophyllotoxin (PPT)2
• Inhibitors of Gli1-mediated transcription in the Hedgehog pathway3
• Protein kinase C θ (PKCθ) inhibitors4
• Indolic non-peptidic HIV protease inhibitors5
• Transient receptor potential cation channel subfamily V member 1 (TRPV1) antagonists6
• Cyclooxygenase-2 (COX-2) and lipoxygenase (LOX) inhibitors7
• 11β-hydroxysteroid dehydrogenase 1 (11β-HSD1) inhibitors8
• Short chain 4-substituted indoles as potent αvβ3 antagonist9
• Ligands of serotonin transporter and 5-HT1A receptors10

Description (简体中文)

Application
Reactant for preparation of:
• Inhibitors of bacterial thymidylate synthase1
• Mimetics of non-alkaloid toxin lignan anticancer and antiviral agent Podophyllotoxin (PPT)2
• Inhibitors of Gli1-mediated transcription in the Hedgehog pathway3
• Protein kinase C θ (PKCθ) inhibitors4
• Indolic non-peptidic HIV protease inhibitors5
• Transient receptor potential cation channel subfamily V member 1 (TRPV1) antagonists6
• Cyclooxygenase-2 (COX-2) and lipoxygenase (LOX) inhibitors7
• 11β-hydroxysteroid dehydrogenase 1 (11β-HSD1) inhibitors8
• Short chain 4-substituted indoles as potent αvβ3 antagonist9
• Ligands of serotonin transporter and 5-HT1A receptors10