Dihydrofolic acid

• Catalog No.: 37296
• CAS Number: 4033-27-6
• M. F.: C19H21N7O6
• M. W.: 443.41334
• Purity: ≥88% (enzymatic)

SYNONYMS

• Title: 二氢叶酸
• IUPAC name: (2S)-2-[(4-{[(2-amino-4-oxo-1,4,7,8-tetrahydropteridin-6-yl)methyl]amino}phenyl)formamido]pentanedioic acid
• IUPAC Traditional name: dihydrofolic acid
• Synonyms: 7,8-Dihydropteroyl-L-glutamic acid; Dihydropteroyl-L-glutamic acid; FAH2

DATABASE IDS

• Beilstein Number: 69017
• CAS Number: 4033-27-6
• MDL Number: MFCD00083619

PROPERTIES

• Empirical Formula (Hill Notation): C19H21N7O6
• Impurities: ≤12% water
• Purity: ≥88% (enzymatic)
• Solubility: 0.1 M NaOH: soluble10 mg/mL, slightly hazy, orange
• GHS Signal Word: Warning
• GHS Hazard statements: H315-H319-H335
• European Hazard Symbols: Irritant (Xi)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves
• GHS Precautionary statements: P261-P305 + P351 + P338
• Risk Statements: 36/37/38
• Safety Statements: 26-36
• German water hazard class: 3

DETAILS

Description (English)

General description
Intermediate in mammalian conversion of dietary folic acid to tetrahydrofolate by dihydrofolate reductase (DHFR). In bacteria, dihydrofolic acid is generated from 7,8-dihydropteroate by dihydrofolate synthetase.
Other Notes
Assay of dihydrofolate reductase1

Description (简体中文)

General description
Intermediate in mammalian conversion of dietary folic acid to tetrahydrofolate by dihydrofolate reductase (DHFR). In bacteria, dihydrofolic acid is generated from 7,8-dihydropteroate by dihydrofolate synthetase.
Other Notes
Assay of dihydrofolate reductase1