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Warfarin™

Catalog No. 45706 Name Sigma Aldrich
CAS Number 81-81-2 Website http://www.sigmaaldrich.com
M. F. C19H16O4 Telephone 1-800-521-8956
M. W. 308.32794 Fax
Purity Email
Storage Chembase ID: 108455

SYNONYMS

Title
华法林™
IUPAC name
4-hydroxy-3-(3-oxo-1-phenylbutyl)-2H-chromen-2-one
IUPAC Traditional name
warfarin
Synonyms
4-羟基-3-(3-氧代-1-苯基丁基)-2H-1-苯并吡喃-2-酮
杀鼠灵钠
4-Hydroxy-3-(3-oxo-1-phenylbutyl)coumarin
Coumafene

DATABASE IDS

CAS Number 81-81-2
MDL Number MFCD00006854
Beilstein Number 8868198
EC Number 201-377-6
PubChem SID 24869276

PROPERTIES

Empirical Formula (Hill Notation) C19H16O4
Grade PESTANAL®, analytical standard
Melting Point 162-164 °C(lit.)
GHS Pictograms GHS08
GHS Signal Word Danger
GHS Hazard statements H360D-H372-H412
European Hazard Symbols Toxic Toxic (T)
MSDS Link Download
GHS Precautionary statements P201-P273-P308 + P313
RID/ADR UN 2811 6.1/PG 1
Risk Statements 61-48/25-52/53
RTECS GN4550000
Safety Statements 53-45-61
Hazard Class 6.1
UN Number 2811
Packing Group 1
German water hazard class 3

DETAILS

Description (English)
Caution
Restricted to professional users. Attention - Avoid exposure - obtain special instructions before use.
Application
Warfarin is an anticoagulant commonly used in the prevention of thrombosis and thromboembolism. Its use is studied in stroke and pulmonary fibrosis patients among many others. It is used to study potential risks and interactions with other drugs and food1.
Biochem/physiol Actions
Warfarin consists of a racemic mixture of two active enantiomers, R- and S- forms. Warfarin is slower-acting than the common anticoagulant heparin. Warfarin inhibits the vitamin K-dependent synthesis of biologically active forms of the calcium-dependent clotting factors II, VII, IX and X. It inhibits regulatory factors protein C, protein S, and protein Z2.
Legal Information
PESTANAL is a registered trademark of Sigma-Aldrich Laborchemikalien GmbH
Warfarin is a trademark of Wisconsin Alumni Research Foundation
Description (简体中文)
Caution
仅限于专业用户。注意 - 避免接触 - 使用前请阅读说明书。
法律信息
PESTANAL 注册商标 Sigma-Aldrich Laborchemikalien GmbH
Warfarin 商标 Wisconsin Alumni Research Foundation

REFERENCES