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5-Aminoindole

Catalog No. 08245 Name Sigma Aldrich
CAS Number 5192-03-0 Website http://www.sigmaaldrich.com
M. F. C8H8N2 Telephone 1-800-521-8956
M. W. 132.16252 Fax
Purity ≥95.0% (NT) Email
Storage Chembase ID: 10443

SYNONYMS

Title
5-氨基吲哚
IUPAC name
1H-indol-5-amine
IUPAC Traditional name
5-aminoindole
Synonyms
5-Indolamine
5-吲哚胺
NSC 61452

DATABASE IDS

PubChem SID 24846038
MDL Number MFCD00005679
EC Number 225-977-2
Beilstein Number 112348
CAS Number 5192-03-0

PROPERTIES

Empirical Formula (Hill Notation) C8H8N2
Grade technical
Purity ≥95.0% (NT)
Melting Point 131-133 °C (dec.)(lit.)
Melting Point 133-136 °C
GHS Pictograms GHS07
GHS Signal Word Warning
GHS Hazard statements H302-H315-H319-H335
European Hazard Symbols Harmful Harmful (Xn)
MSDS Link Download
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
GHS Precautionary statements P261-P305 + P351 + P338
Risk Statements 22-36/37/38
Safety Statements 26
German water hazard class 3

DETAILS

Description (English)
Application
Reactant for preparation of:
• Smac mimetics that bind to the BIR2 domain of the anti-apoptotic protein XIAP1
• Cytotoxic and antimitotic agents2
• Insulin-like growth factor 1 receptor inhibitors3
• Antitumoral agents4
• Factor Xa inhibitor5
• Potential antivascular agents6
• Gli1-mediated transcription in the Hedgehog pathway7
• Inhibitors of receptor tyrosine kinase with antiangiogenic effects8
• PKCθ inhibitors9
• HIV protease inhibitors10
Description (简体中文)
Application
Reactant for preparation of:
• Smac mimetics that bind to the BIR2 domain of the anti-apoptotic protein XIAP1
• Cytotoxic and antimitotic agents2
• Insulin-like growth factor 1 receptor inhibitors3
• Antitumoral agents4
• Factor Xa inhibitor5
• Potential antivascular agents6
• Gli1-mediated transcription in the Hedgehog pathway7
• Inhibitors of receptor tyrosine kinase with antiangiogenic effects8
• PKCθ inhibitors9
• HIV protease inhibitors10

REFERENCES