5-Aminoindole

• Catalog No.: 08245
• CAS Number: 5192-03-0
• M. F.: C8H8N2
• M. W.: 132.16252
• Purity: ≥95.0% (NT)

SYNONYMS

• Title: 5-氨基吲哚
• IUPAC name: 1H-indol-5-amine
• IUPAC Traditional name: 5-aminoindole
• Synonyms: 5-Indolamine; 5-吲哚胺; NSC 61452

DATABASE IDS

• PubChem SID: 24846038
• MDL Number: MFCD00005679
• EC Number: 225-977-2
• Beilstein Number: 112348
• CAS Number: 5192-03-0

PROPERTIES

• Empirical Formula (Hill Notation): C8H8N2
• Grade: technical
• Purity: ≥95.0% (NT)
• Melting Point: 131-133 °C (dec.)(lit.)
• Melting Point: 133-136 °C
• GHS Signal Word: Warning
• GHS Hazard statements: H302-H315-H319-H335
• European Hazard Symbols: Harmful (Xn)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves
• GHS Precautionary statements: P261-P305 + P351 + P338
• Risk Statements: 22-36/37/38
• Safety Statements: 26
• German water hazard class: 3

DETAILS

Description (English)

Application
Reactant for preparation of:
• Smac mimetics that bind to the BIR2 domain of the anti-apoptotic protein XIAP1
• Cytotoxic and antimitotic agents2
• Insulin-like growth factor 1 receptor inhibitors3
• Antitumoral agents4
• Factor Xa inhibitor5
• Potential antivascular agents6
• Gli1-mediated transcription in the Hedgehog pathway7
• Inhibitors of receptor tyrosine kinase with antiangiogenic effects8
• PKCθ inhibitors9
• HIV protease inhibitors10

Description (简体中文)

Application
Reactant for preparation of:
• Smac mimetics that bind to the BIR2 domain of the anti-apoptotic protein XIAP1
• Cytotoxic and antimitotic agents2
• Insulin-like growth factor 1 receptor inhibitors3
• Antitumoral agents4
• Factor Xa inhibitor5
• Potential antivascular agents6
• Gli1-mediated transcription in the Hedgehog pathway7
• Inhibitors of receptor tyrosine kinase with antiangiogenic effects8
• PKCθ inhibitors9
• HIV protease inhibitors10