Adenosine 3′-monophosphate

• Catalog No.: 01950
• CAS Number: 84-21-9
• M. F.: C10H14N5O7P
• M. W.: 347.221221
• Purity: ≥97.0% (HPLC)

SYNONYMS

• Title: 腺苷-3′-磷酸
• IUPAC name: {[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl]oxy}phosphonic acid
• IUPAC Traditional name: adenosine-3'-phosphate
• Synonyms: 3′-AMP; 3′-Adenylic acid; 3′-腺苷酸

DATABASE IDS

• CAS Number: 84-21-9
• EC Number: 201-521-8
• MDL Number: MFCD00005746
• Beilstein Number: 54478

PROPERTIES

• Empirical Formula (Hill Notation): C10H14N5O7P
• Purity: ≥97.0% (HPLC)
• Melting Point: ~210 °C (dec.)
• Optical Rotation: [α]20/D -43±2°, c = 0.5% in 0.5 M Na2HPO4
• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• Storage Temperature: 2-8°C
• German water hazard class: 3

DETAILS

Description (English)

Application
Adenosine 3′-monophosphate (3′-AMP) is a metabolite produced from hydrolysis of 2′,3′-cAMP by a family of metal-dependent phosphodiesterases. 3′-AMP inhibits proliferation of preglomerular vascular smooth muscle cells and glomerular mesangial cells via A2B receptors. 2′,3′-cAMP and 3′-AMP represent a new unexplored pathway for adenosine-based cell regulation.

Description (简体中文)

Application
Adenosine 3′-monophosphate (3′-AMP) is a metabolite produced from hydrolysis of 2′,3′-cAMP by a family of metal-dependent phosphodiesterases. 3′-AMP inhibits proliferation of preglomerular vascular smooth muscle cells and glomerular mesangial cells via A2B receptors. 2′,3′-cAMP and 3′-AMP represent a new unexplored pathway for adenosine-based cell regulation.