Cytochalasin E from Aspergillus clavatus

• Catalog No.: 30390
• CAS Number: 36011-19-5
• M. F.: C28H33NO7
• M. W.: 495.56412
• Purity: ≥99.0% (TLC)

SYNONYMS

• IUPAC name: (1S,7R,9S,13S,14S,16R,17S,18S,19S)-19-benzyl-7-hydroxy-7,9,16,17-tetramethyl-2,4,15-trioxa-20-azatetracyclo[11.8.0.0^1,^1^8.0^1^4,^1^6]henicosa-5,11-diene-3,8,21-trione
• IUPAC Traditional name: (1S,7R,9S,13S,14S,16R,17S,18S,19S)-19-benzyl-7-hydroxy-7,9,16,17-tetramethyl-2,4,15-trioxa-20-azatetracyclo[11.8.0.0^1,^1^8.0^1^4,^1^6]henicosa-5,11-diene-3,8,21-trione

DATABASE IDS

• MDL Number: MFCD00005178
• EC Number: 252-835-7
• Beilstein Number: 1096975
• CAS Number: 36011-19-5

PROPERTIES

• Empirical Formula (Hill Notation): C28H33NO7
• Purity: ≥99.0% (TLC)
• Melting Point: ~226 °C (dec.)
• Solubility: methylene chloride: soluble10 mg/mL, clear, colorless
• GHS Signal Word: Danger
• GHS Hazard statements: H300-H310-H330-H361
• European Hazard Symbols: Highly toxic (T+)
• Personal Protective Equipment: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
• GHS Precautionary statements: P260-P264-P280-P284-P301 + P310-P302 + P350
• RID/ADR: UN 1544 6.1/PG 2
• Risk Statements: 63-26/27/28
• RTECS: HA5360000
• Safety Statements: 28-36/37-45
• Storage Temperature: -20°C
• Hazard Class: 6.1
• UN Number: 1544
• Packing Group: 2
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Cytochalasin E is a cell-permeable fungal toxin that inhibits actin polymerization stimulated by F-actin. Cytochalasin E does not inhibit glucose transport.
Other Notes
Inhibition of actin polymerization in blood platelets by cytochalasins1

Description (简体中文)

Biochem/physiol Actions
Cytochalasin E is a cell-permeable fungal toxin that inhibits actin polymerization stimulated by F-actin. Cytochalasin E does not inhibit glucose transport.
Other Notes
Inhibition of actin polymerization in blood platelets by cytochalasins1