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Creatine monohydrate

Catalog No. 27900 Name Sigma Aldrich
CAS Number 6020-87-7 Website http://www.sigmaaldrich.com
M. F. C4H11N3O3 Telephone 1-800-521-8956
M. W. 149.14844 Fax
Purity ≥99.0% (NT) Email
Storage Chembase ID: 102379

SYNONYMS

Title
肌酸 一水合物
IUPAC name
2-(1-methylcarbamimidamido)acetic acid hydrate
IUPAC Traditional name
creatine hydrate

DATABASE IDS

CAS Number 6020-87-7
MDL Number MFCD00071582
Beilstein Number 7942755
EC Number 200-306-6

PROPERTIES

Empirical Formula (Hill Notation) C4H9N3O2 · H2O
Ignition Residue ≤0.05%
Purity ≥99.0% (NT)
Melting Point ~295 °C (dec.)
GHS Pictograms GHS07
GHS Signal Word Warning
GHS Hazard statements H315-H319-H335
European Hazard Symbols Irritant Irritant (Xi)
MSDS Link Download
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
GHS Precautionary statements P261-P305 + P351 + P338
Risk Statements 36/37/38
RTECS MB7706000
Safety Statements 26
German water hazard class 3

DETAILS

Description (English)
Other Notes
Identification of creatine as a cofactor of thiamine-diphosphate kinase.
Biochem/physiol Actions
Creatine is a nitrogenous compound that acts as a high-energy reservoir for the rapid regeneration of ATP. Approximately 95% of creatine is found in skeletal muscle, primarily as phosphocreatine. Creatine can be acquired through dietary consumption or formed from L-arginine, glycine, and L-methionine in a multi-step reaction that occurs in the kidneys and liver. Creatine is then transported to muscle tissue. Creatine supplementation is used for the enhancement of sports performance, primarily by increasing muscle mass. Creatine is also being investigated as a treatment of neuromuscular diseases, where it may aid in neuroprotection and by improving the cellular bioenergetic state.
Description (简体中文)
Other Notes
Identification of creatine as a cofactor of thiamine-diphosphate kinase.
Biochem/physiol Actions
Creatine is a nitrogenous compound that acts as a high-energy reservoir for the rapid regeneration of ATP. Approximately 95% of creatine is found in skeletal muscle, primarily as phosphocreatine. Creatine can be acquired through dietary consumption or formed from L-arginine, glycine, and L-methionine in a multi-step reaction that occurs in the kidneys and liver. Creatine is then transported to muscle tissue. Creatine supplementation is used for the enhancement of sports performance, primarily by increasing muscle mass. Creatine is also being investigated as a treatment of neuromuscular diseases, where it may aid in neuroprotection and by improving the cellular bioenergetic state.

REFERENCES