Histamine

• Catalog No.: 53290
• CAS Number: 51-45-6
• M. F.: C5H9N3
• M. W.: 111.14506
• Purity: ≥97.0% (NT)

SYNONYMS

• Title: 组胺
• IUPAC name: 2-(1H-imidazol-4-yl)ethan-1-amine
• IUPAC Traditional name: histamine
• Synonyms: 2-(4-Imidazolyl)ethylamine; 2-(4-咪唑基)乙胺

DATABASE IDS

• MDL Number: MFCD00005210
• CAS Number: 51-45-6
• PubChem SID: 24877925
• EC Number: 200-100-6
• Beilstein Number: 2012

PROPERTIES

• Empirical Formula (Hill Notation): C5H9N3
• Purity: ≥97.0% (NT)
• Gene Information: human ... CA1(759), CA2(760), HRH1(3269), HRH2(3274), HRH3(11255), HRH4(59340)rat ... Hrh1(24448), Hrh3(85268)
• Boiling Point: 167 °C/0.8 mmHg(lit.)
• Melting Point: 83-84 °C(lit.)
• Melting Point: ~84 °C
• GHS Signal Word: Danger
• GHS Hazard statements: H301-H315-H317-H319-H334-H335
• European Hazard Symbols: Harmful (Xn)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Faceshields, Gloves
• GHS Precautionary statements: P261-P280-P301 + P310-P305 + P351 + P338-P342 + P311
• RID/ADR: UN 2811 6.1/PG 3
• Risk Statements: 22-36/37/38-42/43
• RTECS: MS1050000
• Safety Statements: 22-26-36/37
• Storage Temperature: -20°C
• Hazard Class: 6.1
• UN Number: 2811
• Packing Group: 3
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Endogenous H1 and H2 histamine receptor agonist; H1 activation mobilizes Ca2+; H2 activation stimulates adenylate cyclase activity in neurons; activates nitric oxide synthetase; potent vasodilator.

Description (简体中文)

Biochem/physiol Actions
内源性 H1 和 H2 组胺受体激动剂；H1 的活化可以使 Ca2+ 移动；H2 的活化可促进神经元中腺苷酸环化酶的活性；活化一氧化氮合成酶；有效的血管舒张剂。