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Histamine

Catalog No. 53290 Name Sigma Aldrich
CAS Number 51-45-6 Website http://www.sigmaaldrich.com
M. F. C5H9N3 Telephone 1-800-521-8956
M. W. 111.14506 Fax
Purity ≥97.0% (NT) Email
Storage Chembase ID: 34689

SYNONYMS

Title
组胺
IUPAC name
2-(1H-imidazol-4-yl)ethan-1-amine
IUPAC Traditional name
histamine
Synonyms
2-(4-Imidazolyl)ethylamine
2-(4-咪唑基)乙胺

DATABASE IDS

MDL Number MFCD00005210
CAS Number 51-45-6
PubChem SID 24877925
EC Number 200-100-6
Beilstein Number 2012

PROPERTIES

Empirical Formula (Hill Notation) C5H9N3
Purity ≥97.0% (NT)
Gene Information human ... CA1(759), CA2(760), HRH1(3269), HRH2(3274), HRH3(11255), HRH4(59340)rat ... Hrh1(24448), Hrh3(85268)
Boiling Point 167 °C/0.8 mmHg(lit.)
Melting Point 83-84 °C(lit.)
Melting Point ~84 °C
GHS Pictograms GHS06
GHS Pictograms GHS08
GHS Signal Word Danger
GHS Hazard statements H301-H315-H317-H319-H334-H335
European Hazard Symbols Harmful Harmful (Xn)
MSDS Link Download
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Faceshields, Gloves
GHS Precautionary statements P261-P280-P301 + P310-P305 + P351 + P338-P342 + P311
RID/ADR UN 2811 6.1/PG 3
Risk Statements 22-36/37/38-42/43
RTECS MS1050000
Safety Statements 22-26-36/37
Storage Temperature -20°C
Hazard Class 6.1
UN Number 2811
Packing Group 3
German water hazard class 3

DETAILS

Description (English)
Biochem/physiol Actions
Endogenous H1 and H2 histamine receptor agonist; H1 activation mobilizes Ca2+; H2 activation stimulates adenylate cyclase activity in neurons; activates nitric oxide synthetase; potent vasodilator.
Description (简体中文)
Biochem/physiol Actions
内源性 H1 和 H2 组胺受体激动剂;H1 的活化可以使 Ca2+ 移动;H2 的活化可促进神经元中腺苷酸环化酶的活性;活化一氧化氮合成酶;有效的血管舒张剂。

REFERENCES