(+)-N,N,N′,N′-Tetramethyl-L-tartaric acid diamide

• Catalog No.: 87953
• CAS Number: 26549-65-5
• M. F.: C8H16N2O4
• M. W.: 204.22364
• Purity: ≥98.0% (sum of enantiomers, HPLC)

SYNONYMS

• Title: (+)-N,N,N′,N′-四甲基-L-酒石酸二酰胺
• IUPAC name: (2R,3R)-2,3-dihydroxy-N,N,N',N'-tetramethylbutanediamide
• IUPAC Traditional name: (2R,3R)-2,3-dihydroxy-N,N,N',N'-tetramethylbutanediamide
• Synonyms: (R,R)-(+)-2,3-二羟基-N,N,N′,N′-四甲基琥珀酰胺; (+)-L-Tartaric acid bis(dimethylamide); (R,R)-(+)-2,3-Dihydroxy-N,N,N′,N′-tetramethylsuccinamide; (+)-L-酒石酸双(二甲酰胺)

DATABASE IDS

• Beilstein Number: 1959244
• CAS Number: 26549-65-5
• MDL Number: MFCD00025672

PROPERTIES

• Grade: purum
• Linear Formula: [-CH(OH)CON(CH3)2]2
• Purity: ≥98.0% (sum of enantiomers, HPLC)
• Melting Point: 184-186 °C(lit.)
• Melting Point: 184-186 °C
• Optical Rotation: [α]20/D +46±2°, c = 3% in ethanol
• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• German water hazard class: 3

DETAILS

Description (English)

Other Notes
Chiral auxiliary; the corresponding acetals of α,β-unsaturated aldehydes and ketones undergo highly regio- and stereoselective reactions at the double bond. Reactions with organoaluminum reagents1; stereoselective bromolactonization2,3; Preparation of a chiral dioxaborolane ligand for cyclopropanation4

Description (简体中文)

Other Notes
手性助剂；α,β-不饱和醛的相应缩醛及酮可在双键位置发生高区域选择性和立体选择性反应。与有机铝试剂反应1；立体选择性溴内酯化2,3；制备手性二氧杂戊硼烷配体，以进行环丙烷化反应4