Isonipecotic acid

• Catalog No.: 80650
• CAS Number: 498-94-2
• M. F.: C6H11NO2
• M. W.: 129.15704
• Purity: ≥97.0% (NT)

SYNONYMS

• Title: 异哌啶酸
• IUPAC name: piperidine-4-carboxylic acid
• IUPAC Traditional name: isonipecotic acid
• Synonyms: 六氢异烟酸; 4-哌啶甲酸; Hexahydroisonicotinic acid; 4-Piperidinecarboxylic acid

DATABASE IDS

• EC Number: 207-872-3
• MDL Number: MFCD00006004
• Beilstein Number: 112553
• CAS Number: 498-94-2
• PubChem SID: 24887575

PROPERTIES

• GHS Signal Word: Warning
• GHS Hazard statements: H315-H319-H335
• European Hazard Symbols: Irritant (Xi)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves
• GHS Precautionary statements: P261-P305 + P351 + P338
• Risk Statements: 36/37/38
• RTECS: NS5150000
• Safety Statements: 26-36
• German water hazard class: 3
• Empirical Formula (Hill Notation): C6H11NO2
• Grade: purum
• Impurities: ≤2% water
• Purity: ≥97.0% (NT)
• Melting Point: >300 °C(lit.)

DETAILS

Description (English)

Application
Reactant for synthesis of:
• Antibiotic nitroxoline derivatives for cathepsin B inhibition1
• Sphingosine-1-phosphate receptor agonists2
• RhoA inhibitors for cardiovascular disease therapy3
• Alkyl piperidine and piperazine hydroxamic acids as HDAC inhibitors
• CHK1 inhibitors4
• IKK2 inhibitors for investigations into rheumatoid arthritis treatment5

Description (简体中文)

Application
Reactant for synthesis of:
• Antibiotic nitroxoline derivatives for cathepsin B inhibition1
• Sphingosine-1-phosphate receptor agonists2
• RhoA inhibitors for cardiovascular disease therapy3
• Alkyl piperidine and piperazine hydroxamic acids as HDAC inhibitors
• CHK1 inhibitors4
• IKK2 inhibitors for investigations into rheumatoid arthritis treatment5