D-Sphingosine

• Catalog No.: 85621
• CAS Number: 123-78-4
• M. F.: C18H37NO2
• M. W.: 299.49188
• Purity: ≥98.0% (TLC)

SYNONYMS

• IUPAC name: (2S,3R)-2-aminooctadec-4-ene-1,3-diol
• IUPAC Traditional name: sphing-4-enine
• Synonyms: (2S,3R,4E)-2-Amino-4-octadecene-1,3-diol; trans-D-erythro-2-Amino-4-octadecene-1,3-diol; 4-Sphingenine

DATABASE IDS

• Beilstein Number: 1727294
• MDL Number: MFCD00036751
• CAS Number: 123-78-4
• EC Number: 204-651-3
• PubChem SID: 24888403

PROPERTIES

• Biological Source: from bovine brain cerebrosides
• Empirical Formula (Hill Notation): C18H37NO2
• Purity: ≥98.0% (TLC)
• Gene Information: rat ... Prkca(24680)
• Solubility: chloroform: soluble20 mg/mL, clear, colorless to very faintly yellow
• Safety Statements: 22-24/25
• Storage Temperature: -20°C
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
A constituent of cell membranes. Precursor of ceramide. Selective inhibitor of protein kinase C, but does not inhibit protein kinase A or myosin light chain kinase. Inhibitor of calmodulin-dependent enzymes.
Other Notes
Potent inhibitor of protein kinase C1
Sales restrictions may apply

Description (简体中文)

Biochem/physiol Actions
A constituent of cell membranes. Precursor of ceramide. Selective inhibitor of protein kinase C, but does not inhibit protein kinase A or myosin light chain kinase. Inhibitor of calmodulin-dependent enzymes.
Other Notes
Potent inhibitor of protein kinase C1
Sales restrictions may apply