Dimethyl 2-oxopropylphosphonate

• Catalog No.: 75948
• CAS Number: 4202-14-6
• M. F.: C5H11O4P
• M. W.: 166.112201
• Purity: ≥90% (GC)

SYNONYMS

• Title: 2-氧代丙基膦酸二甲酯
• IUPAC name: dimethyl (2-oxopropyl)phosphonate
• IUPAC Traditional name: dimethyl 2-oxopropylphosphonate
• Synonyms: 丙酮基磷酸二甲酯; Dimethyl acetonylphosphonate

DATABASE IDS

• PubChem SID: 24886902
• CAS Number: 4202-14-6
• MDL Number: MFCD00008769
• EC Number: 224-110-5
• Beilstein Number: 1766218

PROPERTIES

• Grade: technical
• Linear Formula: CH3COCH2P(O)(OCH3)2
• Purity: ≥90% (GC)
• Boiling Point: 76-79 °C/3 mmHg(lit.)
• Density: 1.202 g/mL at 25 °C(lit.)
• Flash Point: 93 °C
• Flash Point: 199.4 °F
• Refractive Index: n20/D 1.439(lit.)
• Personal Protective Equipment: Eyeshields, Gloves
• Storage Temperature: 2-8°C
• German water hazard class: 3

DETAILS

Description (English)

Other Notes
Wittig-Horner reagent used for the acetonylenation of aldehydes; best conditions for a high E/Z ratio (DBU, LiCl in CH3CN)1,2,3; Synthesis of β-keto phosphonates by γ-alkylation of dianion4

Description (简体中文)

Other Notes
用于醛的丙酮酸化反应的 Wittig-Horner 试剂；得到高 E/Z 比（CH3CN 中的 DBU、LiCl）的最佳条件1,2,3；通过二价阴离子的 γ-烷基化反应合成 β-酮基膦酸酯4