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Angiotensin I human acetate salt hydrate_Molecular_structure_CAS_70937-97-2)
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Angiotensin I human acetate salt hydrate

Catalog No. 10382 Name Sigma Aldrich
CAS Number 70937-97-2 Website http://www.sigmaaldrich.com
M. F. C66H97N17O18 Telephone 1-800-521-8956
M. W. 1416.57948 Fax
Purity ≥97.0% (HPCE) Email
Storage Chembase ID: 132430

SYNONYMS

Title
人血管紧张素 I 乙酸盐 水合物
IUPAC name
(2S)-2-[(2R)-2-[(2S)-2-{[(2S)-1-[(2S)-2-[(2S,3S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-3-carboxypropanamido]-5-carbamimidamidopentanamido]-3-methylbutanamido]-3-(4-hydroxyphenyl)propanamido]-3-methylpentanamido]-3-(1H-imidazol-4-yl)propanoyl]pyrrolidin-2-yl]formamido}-3-phenylpropanamido]-3-(1H-imidazol-4-yl)propanamido]-4-methylpentanoic acid; bis(acetic acid)
IUPAC Traditional name
(2S)-2-[(2R)-2-[(2S)-2-{[(2S)-1-[(2S)-2-[(2S,3S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-3-carboxypropanamido]-5-carbamimidamidopentanamido]-3-methylbutanamido]-3-(4-hydroxyphenyl)propanamido]-3-methylpentanamido]-3-(1H-imidazol-4-yl)propanoyl]pyrrolidin-2-yl]formamido}-3-phenylpropanamido]-3-(1H-imidazol-4-yl)propanamido]-4-methylpentanoic acid; bis(acetic acid)
Synonyms
血管紧张肽 I
Hypertensin I

DATABASE IDS

PubChem SID 24846626
MDL Number MFCD00133091
CAS Number 70937-97-2

PROPERTIES

Empirical Formula (Hill Notation) C62H89N17O14 · xC2H4O2 · yH2O
Impurities ≤10% water
Purity ≥97.0% (HPCE)
Quality synthetic
Gene Information human ... AGT(183)
MSDS Link Download
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Storage Temperature -20°C
German water hazard class 3

DETAILS

Description (English)
Amino Acid Sequence
Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu
Antibody Adsorbant
Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu-OH.2CH3COOH.6H2O
Other Notes
Precursor of angiotensin II, produced by the action of renin on angiotensinogen.; Physiological role of peptides and amines on the regulation of ACTH secretion1
Biochem/physiol Actions
Angiotensin I is a putative neurotransmitter. It is the precursor of angiotensin II and of angiotensin fragment 1-7, which are the hormones involved in regulation of fluid volume and the release of aldosterone.
Description (简体中文)
Amino Acid Sequence
Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu
Antibody Adsorbant
Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu-OH.2CH3COOH.6H2O
Other Notes
Precursor of angiotensin II, produced by the action of renin on angiotensinogen.; Physiological role of peptides and amines on the regulation of ACTH secretion1
Biochem/physiol Actions
血管紧张素 I 是一种假定的神经递质。它是血管紧张素 II 以及血管紧张素片断 1-7 的前体,而这两者是与体液容量调节和醛固酮释放有关的激素。

REFERENCES