Angiotensin I human acetate salt hydrate

• Catalog No.: 10382
• CAS Number: 70937-97-2
• M. F.: C66H97N17O18
• M. W.: 1416.57948
• Purity: ≥97.0% (HPCE)

SYNONYMS

• Title: 人血管紧张素 I 乙酸盐 水合物
• IUPAC name: (2S)-2-[(2R)-2-[(2S)-2-{[(2S)-1-[(2S)-2-[(2S,3S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-3-carboxypropanamido]-5-carbamimidamidopentanamido]-3-methylbutanamido]-3-(4-hydroxyphenyl)propanamido]-3-methylpentanamido]-3-(1H-imidazol-4-yl)propanoyl]pyrrolidin-2-yl]formamido}-3-phenylpropanamido]-3-(1H-imidazol-4-yl)propanamido]-4-methylpentanoic acid; bis(acetic acid)
• IUPAC Traditional name: (2S)-2-[(2R)-2-[(2S)-2-{[(2S)-1-[(2S)-2-[(2S,3S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-3-carboxypropanamido]-5-carbamimidamidopentanamido]-3-methylbutanamido]-3-(4-hydroxyphenyl)propanamido]-3-methylpentanamido]-3-(1H-imidazol-4-yl)propanoyl]pyrrolidin-2-yl]formamido}-3-phenylpropanamido]-3-(1H-imidazol-4-yl)propanamido]-4-methylpentanoic acid; bis(acetic acid)
• Synonyms: 血管紧张肽 I; Hypertensin I

DATABASE IDS

• PubChem SID: 24846626
• MDL Number: MFCD00133091
• CAS Number: 70937-97-2

PROPERTIES

• Empirical Formula (Hill Notation): C62H89N17O14 · xC2H4O2 · yH2O
• Impurities: ≤10% water
• Purity: ≥97.0% (HPCE)
• Quality: synthetic
• Gene Information: human ... AGT(183)
• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• Storage Temperature: -20°C
• German water hazard class: 3

DETAILS

Description (English)

Amino Acid Sequence
Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu
Antibody Adsorbant
Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu-OH.2CH3COOH.6H2O
Other Notes
Precursor of angiotensin II, produced by the action of renin on angiotensinogen.; Physiological role of peptides and amines on the regulation of ACTH secretion1
Biochem/physiol Actions
Angiotensin I is a putative neurotransmitter. It is the precursor of angiotensin II and of angiotensin fragment 1-7, which are the hormones involved in regulation of fluid volume and the release of aldosterone.

Description (简体中文)

Amino Acid Sequence
Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu
Antibody Adsorbant
Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu-OH.2CH3COOH.6H2O
Other Notes
Precursor of angiotensin II, produced by the action of renin on angiotensinogen.; Physiological role of peptides and amines on the regulation of ACTH secretion1
Biochem/physiol Actions
血管紧张素 I 是一种假定的神经递质。它是血管紧张素 II 以及血管紧张素片断 1-7 的前体，而这两者是与体液容量调节和醛固酮释放有关的激素。