Thyrotropin releasing hormone

• Catalog No.: 83177
• CAS Number: 24305-27-9
• M. F.: C16H22N6O4
• M. W.: 362.38368
• Purity: ≥85% peptide basis

SYNONYMS

• Title: 促甲状腺素释放激素
• IUPAC name: (2S)-1-[(2S)-3-(1H-imidazol-4-yl)-2-{[(2S)-5-oxopyrrolidin-2-yl]formamido}propanoyl]pyrrolidine-2-carboxamide
• IUPAC Traditional name: (2S)-1-[(2S)-3-(1H-imidazol-4-yl)-2-{[(2S)-5-oxopyrrolidin-2-yl]formamido}propanoyl]pyrrolidine-2-carboxamide
• Synonyms: L-焦谷氨酰-L-组氨酰-L-脯氨酰胺; Thyroliberin; pGlu-His-Pro 酰胺; TRF; TRH; 促甲状腺素释放素; L-Pyroglutamyl-L-histidyl-L-prolinamide; pGlu-His-Pro amide

DATABASE IDS

• MDL Number: MFCD00038640
• Beilstein Number: 770238
• EC Number: 246-143-4
• CAS Number: 24305-27-9

PROPERTIES

• Impurities: ≤5% water
• Purity: ≥85% peptide basis
• Purity: ≥98.0% (HPLC)
• Empirical Formula (Hill Notation): C16H22N6O4
• Gene Information: human ... TRH(7200)
• Solubility: H2O: soluble10 mg/mL, clear, colorless
• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• RTECS: TW3580000
• Storage Temperature: -20°C
• German water hazard class: 2

DETAILS

Description (English)

Amino Acid Sequence
Glp-His-Pro-NH2
Biochem/physiol Actions
Stimulates the production of thyrotropin (TSH) and its secretion from the anterior pituitary.
Other Notes
Review1; TRH and phorbol esters stimulate sphingomyelin synthesis in GH3 pituitary cells2

Description (简体中文)

Amino Acid Sequence
Glp-His-Pro-NH2
Biochem/physiol Actions
促进垂体前叶生成和分泌促甲状腺素 (TSH)。
Other Notes
Review1; TRH and phorbol esters stimulate sphingomyelin synthesis in GH3 pituitary cells2