Forskolin

• Catalog No.: 47735
• CAS Number: 66575-29-9
• M. F.: C22H34O7
• M. W.: 410.50116
• Purity: ≥98.0% (TLC)

SYNONYMS

• IUPAC name: (3R,4aR,5S,6S,6aS,10S,10aR,10bS)-3-ethenyl-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-dodecahydro-1H-naphtho[2,1-b]pyran-5-yl acetate
• IUPAC Traditional name: forskolin
• Synonyms: Colforsin; Coleonol; 7β-Acetoxy-8,13-epoxy-1α,6β,9α-trihydroxylabd-14-en-11-one

DATABASE IDS

• Beilstein Number: 1692716
• EC Number: 266-410-9
• MDL Number: MFCD00082317
• CAS Number: 66575-29-9

PROPERTIES

• Biological Source: from Coleus forskohlii
• Empirical Formula (Hill Notation): C22H34O7
• Purity: ≥98.0% (TLC)
• GHS Signal Word: Warning
• GHS Hazard statements: H312
• European Hazard Symbols: Harmful (Xn)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves
• GHS Precautionary statements: P280
• Risk Statements: 21
• RTECS: QL6150000
• Safety Statements: 22-36/37
• Storage Temperature: -20°C
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Cell-permeable diterpenoid that possesses anti-hypertensive, positive inotropic, and adenylyl cyclase activating properties. Many of its biological effects are due to its activation of adenylyl cyclase and the resulting increase in intracellular cAMP concentration.1 Forskolin effects calcium currents and inhibits MAP kinase.

Description (简体中文)

Biochem/physiol Actions
Cell-permeable diterpenoid that possesses anti-hypertensive, positive inotropic, and adenylyl cyclase activating properties. Many of its biological effects are due to its activation of adenylyl cyclase and the resulting increase in intracellular cAMP concentration.1 Forskolin effects calcium currents and inhibits MAP kinase.