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Forskolin

Catalog No. 47735 Name Sigma Aldrich
CAS Number 66575-29-9 Website http://www.sigmaaldrich.com
M. F. C22H34O7 Telephone 1-800-521-8956
M. W. 410.50116 Fax
Purity ≥98.0% (TLC) Email
Storage Chembase ID: 2315

SYNONYMS

IUPAC name
(3R,4aR,5S,6S,6aS,10S,10aR,10bS)-3-ethenyl-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-dodecahydro-1H-naphtho[2,1-b]pyran-5-yl acetate
IUPAC Traditional name
forskolin
Synonyms
Colforsin
Coleonol
7β-Acetoxy-8,13-epoxy-1α,6β,9α-trihydroxylabd-14-en-11-one

DATABASE IDS

Beilstein Number 1692716
EC Number 266-410-9
MDL Number MFCD00082317
CAS Number 66575-29-9

PROPERTIES

Biological Source from Coleus forskohlii
Empirical Formula (Hill Notation) C22H34O7
Purity ≥98.0% (TLC)
GHS Pictograms GHS07
GHS Signal Word Warning
GHS Hazard statements H312
European Hazard Symbols Harmful Harmful (Xn)
MSDS Link Download
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
GHS Precautionary statements P280
Risk Statements 21
RTECS QL6150000
Safety Statements 22-36/37
Storage Temperature -20°C
German water hazard class 3

DETAILS

Description (English)
Biochem/physiol Actions
Cell-permeable diterpenoid that possesses anti-hypertensive, positive inotropic, and adenylyl cyclase activating properties. Many of its biological effects are due to its activation of adenylyl cyclase and the resulting increase in intracellular cAMP concentration.1 Forskolin effects calcium currents and inhibits MAP kinase.
Description (简体中文)
Biochem/physiol Actions
Cell-permeable diterpenoid that possesses anti-hypertensive, positive inotropic, and adenylyl cyclase activating properties. Many of its biological effects are due to its activation of adenylyl cyclase and the resulting increase in intracellular cAMP concentration.1 Forskolin effects calcium currents and inhibits MAP kinase.

REFERENCES