(R)-(+)-1-Amino-2-(methoxymethyl)pyrrolidine

• Catalog No.: 08394
• CAS Number: 72748-99-3
• M. F.: C6H14N2O
• M. W.: 130.18816
• Purity: ≥95.0% (sum of enantiomers, GC)

SYNONYMS

• Title: (R)-(+)-1-氨基-2-(甲氧基甲基)吡咯烷
• IUPAC name: (2R)-2-(methoxymethyl)pyrrolidin-1-amine
• IUPAC Traditional name: (2R)-2-(methoxymethyl)pyrrolidin-1-amine
• Synonyms: RAMP

DATABASE IDS

• MDL Number: MFCD00010622
• CAS Number: 72748-99-3
• Beilstein Number: 4229866
• PubChem SID: 24846167

PROPERTIES

• Empirical Formula (Hill Notation): C6H14N2O
• Grade: purum
• Optical Purity: enantiomeric ratio: ≥98:2
• Purity: ≥95.0% (sum of enantiomers, GC)
• Boiling Point: 186-187 °C(lit.)
• Density: 0.978 g/mL at 25 °C(lit.)
• Flash Point: 72 °C
• Flash Point: 161.6 °F
• Optical Rotation: [α]20/D +80±3°, neat
• Refractive Index: n20/D 1.464(lit.)
• GHS Signal Word: Warning
• GHS Hazard statements: H315-H319-H335
• European Hazard Symbols: Irritant (Xi)
• Personal Protective Equipment: Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
• GHS Precautionary statements: P261-P305 + P351 + P338
• Risk Statements: 36/37/38
• Safety Statements: 26-36
• Storage Temperature: 2-8°C
• German water hazard class: 3

DETAILS

Description (English)

Other Notes
Chiral auxiliary for the preparation of chiral hydrazones, which can be alkylated stereoselectively and used in Michael additions1,2,3; Transformation of aldehydes to chiral amines4

Description (简体中文)

Other Notes
该手性助剂用于制备手性腙，手性腙可发生立体选择性烷基化反应，也可参与 Michael 加成反应1,2,3；可将醛转化为手性胺4