Tubercidin

• Catalog No.: 93747
• CAS Number: 69-33-0
• M. F.: C11H14N4O4
• M. W.: 266.25326
• Purity: ≥99.0% (HPLC)

SYNONYMS

• IUPAC name: (2R,3R,4S,5R)-2-{4-amino-7H-pyrrolo[2,3-d]pyrimidin-7-yl}-5-(hydroxymethyl)oxolane-3,4-diol
• IUPAC Traditional name: tubercidin
• Synonyms: 7-Deazaadenosine

DATABASE IDS

• MDL Number: MFCD00056012
• EC Number: 200-703-4
• Beilstein Number: 38498
• CAS Number: 69-33-0

PROPERTIES

• Biological Source: from Streptomyces tubercidicus
• Empirical Formula (Hill Notation): C11H14N4O4
• Purity: ≥99.0% (HPLC)
• GHS Signal Word: Danger
• GHS Hazard statements: H300
• European Hazard Symbols: Highly toxic (T+)
• Personal Protective Equipment: Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
• GHS Precautionary statements: P264-P301 + P310
• RID/ADR: UN 3462 6.1/PG 2
• Risk Statements: 28
• RTECS: UY8870000
• Safety Statements: 36/37/39-45
• Hazard Class: 6.1
• UN Number: 3462
• Packing Group: 2
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Toxic adenosine analog with antiviral,1 antitrypanosomal,2 and antifungal functions. Mode of action: Inhibits multiple metabolic processes, including RNA processing, nucleic acid synthesis, protein synthesis, and methylation of tRNA through intracellular incorporation into nucleic acids. Tubercidin acts as a plant antifungal,3 inhibits mammalian SAH hydrolase (SAHH),4 and blocks purine biosynthesis in Candida famata.5

Description (简体中文)

Biochem/physiol Actions
Toxic adenosine analog with antiviral,1 antitrypanosomal,2 and antifungal functions. Mode of action: Inhibits multiple metabolic processes, including RNA processing, nucleic acid synthesis, protein synthesis, and methylation of tRNA through intracellular incorporation into nucleic acids. Tubercidin acts as a plant antifungal,3 inhibits mammalian SAH hydrolase (SAHH),4 and blocks purine biosynthesis in Candida famata.5