Clarithromycin

• Catalog No.: 16632
• CAS Number: 81103-11-9
• M. F.: C38H69NO13
• M. W.: 747.95336

SYNONYMS

• IUPAC name: (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy}-14-ethyl-12,13-dihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy}-7-methoxy-3,5,7,9,11,13-hexamethyl-1-oxacyclotetradecane-2,10-dione
• IUPAC Traditional name: clarithromycin

DATABASE IDS

• MDL Number: MFCD00865140
• CAS Number: 81103-11-9

PROPERTIES

• Empirical Formula (Hill Notation): C38H69NO13
• Pharmacopeia Traceability: traceable to BP 833
• Pharmacopeia Traceability: traceable to PhEur Y0000320
• Pharmacopeia Traceability: traceable to USP 1134379
• GHS Signal Word: Warning
• GHS Hazard statements: H302
• European Hazard Symbols: Harmful (Xn)
• Risk Statements: 22
• RTECS: KF4997000
• Storage Temperature: 2-8°C
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Clarithromycin is a macrolide antibiotic. It prevents bacterial growth by interfering with protein synthesis. Clarithromycin is an acid-stable version of erythromycin and is particularly effective against gram-negative bacteria.1 It has a short half-life2, however its metabolite, 14-hydroxy clarithromycin is nearly twice as active as clarithromycin against certain bacteria.3

Description (简体中文)

Biochem/physiol Actions
Clarithromycin is a macrolide antibiotic. It prevents bacterial growth by interfering with protein synthesis. Clarithromycin is an acid-stable version of erythromycin and is particularly effective against gram-negative bacteria.1 It has a short half-life2, however its metabolite, 14-hydroxy clarithromycin is nearly twice as active as clarithromycin against certain bacteria.3