Hydrocortisone

• Catalog No.: 91506
• CAS Number: 50-23-7
• M. F.: C21H30O5
• M. W.: 362.4599

SYNONYMS

• Title: 氢化可的松
• IUPAC name: (1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadec-6-en-5-one
• IUPAC Traditional name: hydrocortisone
• Synonyms: 11β,17α,21-三羟基孕甾-4-烯-3,20-二酮; 皮质醇; Cortisol; 17-Hydroxycorticosterone; 11β,17α,21-Trihydroxypregn-4-ene-3,20-dione; 4-Pregnene-11β,17α,21-triol-3,20-dione; Kendall’s compound F; Reichstein’s substance M; 17-羟基皮质甾酮; 4-孕烯-11β,17α,21-三醇-3,20-二酮; 氢化泼尼松龙; 氢化皮质酮

DATABASE IDS

• MDL Number: MFCD00011654
• Beilstein Number: 1354819
• CAS Number: 50-23-7
• EC Number: 200-020-1

PROPERTIES

• Empirical Formula (Hill Notation): C21H30O5
• Pharmacopeia Traceability: traceable to BP 576
• Pharmacopeia Traceability: traceable to PhEur H1300000
• Pharmacopeia Traceability: traceable to USP 1316004
• Melting Point: 211-214 °C(lit.)
• GHS Signal Word: Warning
• GHS Hazard statements: H361
• European Hazard Symbols: Harmful (Xn)
• GHS Precautionary statements: P281
• Risk Statements: 63
• RTECS: GM8925000
• Safety Statements: 36/37
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Primary glucocorticoid secreted by the adrenal cortex. It has three times the anti-inflammatory potency of corticosterone but much lower Na2+ retention potency.

Description (简体中文)

Biochem/physiol Actions
肾上腺皮质分泌的原发性糖皮质激素。消炎效果是皮质酮的三倍，但 Na2+ 保留性能比皮质酮低。