Quercetin dihydrate

• Catalog No.: 00200595
• CAS Number: 6151-25-3
• M. F.: C15H14O9
• M. W.: 338.26626

SYNONYMS

• Title: 槲皮素 二水合物
• IUPAC name: 2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-4H-chromen-4-one dihydrate
• IUPAC Traditional name: quercetin dihydrate
• Synonyms: 2-(3,4-二羟苯基)-3,5,7-三羟基-4H-1-苯并吡喃-4-酮 二水合物; 3,3′,4′,5,7-五羟基黄酮 二水合物; 3,3′,4′,5,7-Pentahydroxyflavone dihydrate; 2-(3,4-Dihydroxyphenyl)-3,5,7-trihydroxy-4H-1-benzopyran-4-one dihydrate

DATABASE IDS

• EC Number: 204-187-1
• Color Index Number: 75670
• MDL Number: MFCD00149487
• Beilstein Number: 317313
• CAS Number: 6151-25-3

PROPERTIES

• Empirical Formula (Hill Notation): C15H10O7 · 2H2O
• Grade: primary reference standard
• Melting Point: >300 °C(lit.)
• GHS Signal Word: Danger
• GHS Hazard statements: H301
• European Hazard Symbols: Toxic (T)
• GHS Precautionary statements: P301 + P310
• Risk Statements: 25
• RTECS: LK8950000
• Safety Statements: 45
• German water hazard class: 3

DETAILS

Description (English)

Application
Reference standard in the analysis of herbal medicinal products.
General description
Produced and qualified by HWI AnalytikExact content by quantitative NMR can be found on the certificate
Biochem/physiol Actions
Quercetin dihydrate is a flavonoid with anticancer activity. Quercetin is a mitochondrial ATPase and phosphodiesterase inhibitor. It Inhibits PI3-kinase activity and slightly inhibits PIP kinase activity. Quercetin has antiproliferative effects on cancer cell lines, reduces cancer cell growth via type II estrogen receptors, and arrests human leukemic T cells in late G1 phase of the cell cycle.

Description (简体中文)

Application
草药产品分析的标准品。
General description
由 HWI Analytik 生产和检验 证书上注明了由定量 NMR 确定的准确含量
Biochem/physiol Actions
槲皮素二水合物是具有抗癌活性的黄酮类化合物。槲皮素为线粒体 ATP 酶和磷酸二酯酶抑制剂。它可抑制 PI3 激酶活性并且轻微抑制 PIP 激酶活性。槲皮素对癌细胞系具有抗增殖作用，通过 II 型雌激素受体降低癌细胞的生长，并且阻滞细胞周期晚期 G1 相中人类白血病 T 细胞。