Cocaine hydrochloride

• Catalog No.: 51621
• CAS Number: 53-21-4
• M. F.: C17H22ClNO4
• M. W.: 339.81388
• Purity: ≥98.5% (HPLC)

SYNONYMS

• Title: 可卡因 盐酸盐
• IUPAC name: methyl (1R,2R,3S,5S)-3-(benzoyloxy)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate hydrochloride
• IUPAC Traditional name: cocaine hydrochloride
• Synonyms: Ecgonine methyl ester benzoate hydrochloride; 苯甲酰甲基芽子碱 盐酸盐

DATABASE IDS

• CAS Number: 53-21-4
• EC Number: 200-167-1
• MDL Number: MFCD00058119

PROPERTIES

• Empirical Formula (Hill Notation): C17H21NO4 · HCl
• Grade: analytical standard, for drug analysis
• Purity: ≥98.5% (HPLC)
• Shelf Life: (limited shelf life, expiry date on the label)
• Drug Control: USDEA Schedule II; Home Office Schedule 2; regulated under CDSA - not available from Sigma-Aldrich Canada
• GHS Signal Word: Danger
• GHS Hazard statements: H301-H317-H360
• European Hazard Symbols: Toxic (T)
• Personal Protective Equipment: Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
• GHS Precautionary statements: P201-P280-P301 + P310-P308 + P313
• Risk Statements: 60-25-43
• RTECS: YM3050000
• Safety Statements: 53-22-36/37-45
• Storage Temperature: 2-8°C
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Inhibits the dopamine, norepinephrine, and serotonin transporters with Kis of about 300 nM, 900 nM, and 400 nM, respectively. Unlike amphetamines, it has no effect on catecholamine release.

Description (简体中文)

Biochem/physiol Actions
分别以大约 300nM、900nM 和 400nM 的 Kis 抑制多巴胺、去甲肾上腺素和 5-羟色胺转运蛋白。不同于苯异丙胺，它不会影响儿茶酚胺的释放。