α,α-Diphenyl-L-prolinol

• Catalog No.: 43182
• CAS Number: 112068-01-6
• M. F.: C17H19NO
• M. W.: 253.33886
• Purity: ≥99.0% (sum of enantiomers, HPLC)

SYNONYMS

• Title: (S)-(+)-α,α-二苯基脯氨醇
• IUPAC name: diphenyl(2S)-pyrrolidin-2-ylmethanol
• IUPAC Traditional name: diphenyl(2S)-pyrrolidin-2-ylmethanol
• Synonyms: (S)-2-(二苯基羟甲基)吡咯烷; (S)-2-(Diphenylhydroxymethyl)pyrrolidine; (S)-α,α-Diphenyl-2-pyrrolidinemethanol; (S)-α,α-二苯基-2-吡咯烷甲醇

DATABASE IDS

• CAS Number: 112068-01-6
• Beilstein Number: 6060893
• MDL Number: MFCD00075506

PROPERTIES

• Empirical Formula (Hill Notation): C17H19NO
• Grade: purum
• Optical Purity: enantiomeric ratio: ≥99.5:0.5 (HPLC)
• Purity: ≥99.0% (sum of enantiomers, HPLC)
• Melting Point: 77-80 °C(lit.)
• Melting Point: 77-80 °C
• Optical Rotation: [α]20/D -69±2°, c = 3% in chloroform
• European Hazard Symbols: Irritant (Xi)
• Risk Statements: 36/37/38
• Safety Statements: 26-36
• German water hazard class: 3

DETAILS

Description (English)

Other Notes
The cyclic borane adduct, an oxazaborolidine, is an efficient catalyst for enantioselective reductions of ketones with borane (CBS-reduction)1,2,3,4

Description (简体中文)

Other Notes
环硼烷加合物--噁唑硼烷是一种高效催化剂，用于酮与硼烷的不对称还原反应（CBS-还原反应）1,2,3,4