Citrinin

• Catalog No.: 00302
• CAS Number: 518-75-2
• M. F.: C13H14O5
• M. W.: 250.24726
• Purity: ≥98.0% (TLC)

SYNONYMS

• Title: 桔霉素
• IUPAC name: (3R,4S)-8-hydroxy-3,4,5-trimethyl-6-oxo-4,6-dihydro-3H-2-benzopyran-7-carboxylic acid
• IUPAC Traditional name: antimycin
• Synonyms: 4,6-Dihydro-8-hydroxy-3,4,5-trimethyl-6-oxo-3H-2-benzopyran-7-carboxylic acid; 桔青霉素

DATABASE IDS

• Beilstein Number: 5282243
• MDL Number: MFCD00006912
• CAS Number: 518-75-2
• EC Number: 208-257-2

PROPERTIES

• Biological Source: from Penicillium citrinum
• Empirical Formula (Hill Notation): C13H14O5
• Purity: ≥98.0% (TLC)
• GHS Signal Word: Danger
• GHS Hazard statements: H301-H311-H331-H351
• European Hazard Symbols: Toxic (T)
• GHS Precautionary statements: P261-P280-P301 + P310-P311
• RID/ADR: UN 3462 6.1/PG 3
• Risk Statements: 23/24/25-40
• RTECS: DJ2275000
• Safety Statements: 26-36/37/39-45
• Storage Temperature: 2-8°C
• Hazard Class: 6.1
• UN Number: 3462
• Packing Group: 3
• German water hazard class: 3
• Personal Protective Equipment: Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges

DETAILS

Description (English)

Biochem/physiol Actions
A mycotoxin found in grains and animal feed that nephrotoxic and is a teratogen in rodents, reducing blastocyst cell number, embryonic survival, and neonatial weight and increasing fetal abnormalities. It′s cytotoxicity to cells in culture are associated with the production of reactive oxygen species, the activation of mitochondrial apoptotic pathways, and the inhibition of antiapoptotic phosphorylation pathways.

Description (简体中文)

Biochem/physiol Actions
A mycotoxin found in grains and animal feed that nephrotoxic and is a teratogen in rodents, reducing blastocyst cell number, embryonic survival, and neonatial weight and increasing fetal abnormalities. It′s cytotoxicity to cells in culture are associated with the production of reactive oxygen species, the activation of mitochondrial apoptotic pathways, and the inhibition of antiapoptotic phosphorylation pathways.